C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: roundabout homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022883 Robo1 10090 + 16:72663149-73046095 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023600 Robo1-001 72663149-73046095 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023600
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023600 1.787±1.67 18.188±3.84 0.931±0.26 11.188±6.37 1.059±0.49 1.028±0.53 0.250±0.11 0.637±0.22 1.108±0.60 2.026±0.33 0.115±0.03 4.801±1.73 0.703±0.21 0.523±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00083H CIL_00083H_0002 VISTA 16:72385637-72988302
CIL_00031Z CIL_00031Z_0002 CGP 16:72663149-74411825

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002042 IEA cell migration involved in sprouting angiogenesis
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007411 IMP axon guidance
GO:0008285 IMP negative regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0021836 IEA chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0030275 IEA LRR domain binding
GO:0030673 IDA axolemma
GO:0033600 IEA negative regulation of mammary gland epithelial cell proliferation
GO:0035385 IEA Roundabout signaling pathway
GO:0042802 IEA identical protein binding
GO:0050772 IEA positive regulation of axonogenesis
GO:0050925 IEA negative regulation of negative chemotaxis
GO:0060763 IMP mammary duct terminal end bud growth
GO:0070100 IEA negative regulation of chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026784 robo1 roundabout homolog 1 protein_coding Danio_rerio
ENSG00000169855 ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) protein_coding Homo_sapiens

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