C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E26 avian leukemia oncogene 2, 3' domain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022895 Ets2 10090 + 16:95702075-95721051 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023612 Ets2-001 95702075-95721051 protein_coding
  ENSMUST00000140544 Ets2-005 95715854-95719122 retained_intron
  ENSMUST00000143554 Ets2-004 95702500-95712564 retained_intron
  ENSMUST00000145509 Ets2-003 95702455-95710163 retained_intron
  ENSMUST00000155226 Ets2-002 95706339-95716072 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023612ENSMUST00000143554ENSMUST00000145509ENSMUST00000155226
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023612 7.790±0.81 13.061±0.72 10.263±5.60 4.764±2.28 14.552±4.32 37.778±2.98 7.754±2.35 9.356±3.70 4.958±2.00 36.250±17.56 5.714±3.08 19.685±4.77 50.923±10.06 0.462±0.23
ENSMUST00000143554 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.361±0.00 75.978±0.00 0.305±0.00
ENSMUST00000145509 N/A 38.084±10.72 N/A N/A 30.066±2.79 47.320±8.08 N/A N/A 4.786±0.00 69.152±22.30 N/A 38.245±5.26 N/A N/A
ENSMUST00000155226 15.026±2.43 N/A N/A 23.457±0.00 N/A N/A N/A N/A N/A 32.612±0.00 N/A 18.010±4.06 110.142±33.33 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003GI CIL_0003GI_0002 CGP 16:95359169-95721051
CIL_0007UB CIL_0007UB_0002 VISTA 16:95547910-96149564
CIL_0000XL CIL_0000XL_0002 CGP 16:95702075-95990960

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0030154 IBA cell differentiation
GO:0035259 IEA glucocorticoid receptor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018308 ets2 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) protein_coding Danio_rerio
ENSG00000157557 ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 protein_coding Homo_sapiens

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