C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: karyopherin (importin) alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022905 Kpna1 10090 + 16:35978750-36037131 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004054 Kpna1-001 35983315-36037131 protein_coding
  ENSMUST00000172534 Kpna1-004 36013797-36035131 nonsense_mediated_decay
  ENSMUST00000172991 Kpna1-010 35978750-36003408 retained_intron
  ENSMUST00000173469 Kpna1-008 36021644-36031774 retained_intron
  ENSMUST00000173555 Kpna1-005 35983582-36012913 protein_coding
  ENSMUST00000173641 Kpna1-009 36019380-36033868 protein_coding
  ENSMUST00000173696 Kpna1-003 36000187-36033908 nonsense_mediated_decay
  ENSMUST00000173715 Kpna1-002 35983325-36005188 retained_intron
  ENSMUST00000174500 Kpna1-006 35983354-36019280 nonsense_mediated_decay
  ENSMUST00000174737 Kpna1-007 36000253-36021645 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004054ENSMUST00000172534ENSMUST00000173555
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004054 5.890±1.01 4.572±1.10 8.592±0.41 13.194±3.03 6.570±2.63 4.059±0.93 10.176±2.13 4.233±0.64 7.622±2.84 5.611±0.91 28.335±1.34 5.346±1.63 11.241±2.99 2.818±1.56
ENSMUST00000172534 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.355±1.05 N/A 4.815±0.12
ENSMUST00000173555 N/A N/A N/A 115.281±0.00 N/A N/A N/A N/A N/A N/A N/A 66.044±0.00 92.175±37.58 29.545±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006606 IEA protein import into nucleus
GO:0008565 IEA protein transporter activity
GO:0030425 ISS dendrite
GO:0042307 ISS positive regulation of protein import into nucleus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016360 kpna1 karyopherin alpha 1 (importin alpha 5) protein_coding Danio_rerio
ENSG00000114030 KPNA1 karyopherin alpha 1 (importin alpha 5) protein_coding Homo_sapiens

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