C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022997 Wnt1 10090 + 15:98789857-98793837 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023734 Wnt1-001 98789857-98793837 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENSMUST00000023734
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENSMUST00000023734 0.098±0.05 0.021±0.01 0.025±0.01 0.440±0.21 0.335±0.12 0.019±0.01 0.010±0.00 0.015±0.00 0.010±0.00 0.018±0.00 0.092±0.04 0.039±0.00 0.181±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00033L CIL_00033L_0003 CGP 15:98771753-98793837
CIL_00000D CIL_00000D_0002 CGP 15:98789857-98807925

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000578 IMP embryonic axis specification
GO:0001658 IGI branching involved in ureteric bud morphogenesis
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0005102 TAS receptor binding
GO:0005109 IBA frizzled binding
GO:0005125 IDA cytokine activity
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IBA extracellular space
GO:0005737 IEA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0007165 TAS signal transduction
GO:0007267 IDA cell-cell signaling
GO:0007520 IDA myoblast fusion
GO:0008284 IDA positive regulation of cell proliferation
GO:0009611 IEA response to wounding
GO:0009887 TAS organ morphogenesis
GO:0009986 IDA cell surface
GO:0010592 IEA positive regulation of lamellipodium assembly
GO:0010812 IEA negative regulation of cell-substrate adhesion
GO:0014902 IGI myotube differentiation
GO:0016055 IDA Wnt signaling pathway
GO:0019904 IPI protein domain specific binding
GO:0021527 IGI spinal cord association neuron differentiation
GO:0021536 IGI diencephalon development
GO:0021551 IMP central nervous system morphogenesis
GO:0021588 IMP cerebellum formation
GO:0021797 IGI forebrain anterior/posterior pattern specification
GO:0022004 IMP midbrain-hindbrain boundary maturation during brain development
GO:0022037 IMP metencephalon development
GO:0022408 IEA negative regulation of cell-cell adhesion
GO:0030509 ISO BMP signaling pathway
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IEA negative regulation of BMP signaling pathway
GO:0030579 IDA ubiquitin-dependent SMAD protein catabolic process
GO:0030901 IMP midbrain development
GO:0030917 IMP midbrain-hindbrain boundary development
GO:0031100 IEA organ regeneration
GO:0033077 IDA T cell differentiation in thymus
GO:0042472 IGI inner ear morphogenesis
GO:0042770 IEA signal transduction in response to DNA damage
GO:0043568 IEA positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044336 IEA canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0045596 IMP negative regulation of cell differentiation
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045747 IEA positive regulation of Notch signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048663 IMP neuron fate commitment
GO:0048664 IMP neuron fate determination
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060061 IMP Spemann organizer formation
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060348 ISS bone development
GO:0061184 IEA positive regulation of dermatome development
GO:0070365 IEA hepatocyte differentiation
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0071425 IDA hematopoietic stem cell proliferation
GO:0090344 IEA negative regulation of cell aging
GO:2000059 IDA negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055554 wnt1 wingless-type MMTV integration site family, member 1 protein_coding Danio_rerio
ENSG00000125084 WNT1 wingless-type MMTV integration site family, member 1 protein_coding Homo_sapiens

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