C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 4, group A, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023034 Nr4a1 10090 + 15:101266846-101274792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023779 Nr4a1-201 101266846-101274792 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023779
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023779 2.730±0.60 54.570±20.78 4.339±1.28 2.903±2.47 8.439±2.51 5.792±0.70 4.307±2.01 1.227±0.28 0.314±0.10 13.810±1.66 19.010±18.29 23.299±13.58 2.039±1.90 17.155±7.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006K0 CIL_0006K0_0002 CGP 15:101224207-101274792
CIL_0006JQ CIL_0006JQ_0002 CGP 15:101266846-101290934

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0002042 IEA cell migration involved in sprouting angiogenesis
GO:0003677 IDA DNA binding
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IMP apoptotic process
GO:0008270 IEA zinc ion binding
GO:0010035 ISA response to inorganic substance
GO:0030522 IEA intracellular receptor signaling pathway
GO:0035767 IEA endothelial cell chemotaxis
GO:0035914 IMP skeletal muscle cell differentiation
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA sequence-specific DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0071310 IDA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000796 nr4a1 nuclear receptor subfamily 4, group A, member 1 protein_coding Danio_rerio
ENSG00000123358 NR4A1 nuclear receptor subfamily 4, group A, member 1 protein_coding Homo_sapiens

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