C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: granzyme A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023132 Gzma 10090 - 13:113093825-113100979 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023897 Gzma-201 113093825-113100979 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023897
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023897 1.047±0.42 0.318±0.14 2.145±0.22 0.105±0.00 1.884±0.36 0.515±0.11 0.917±0.62 0.532±0.30 1.260±2.35 6.247±0.84 0.107±0.10 0.464±0.16 0.543±0.75 0.125±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VR CIL_0007VR_0002 VISTA 13:112943520-113548070

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004252 ISS serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005634 IDA nucleus
GO:0006915 IEA apoptotic process
GO:0008236 IDA serine-type peptidase activity
GO:0019835 IEA cytolysis
GO:0032078 ISS negative regulation of endodeoxyribonuclease activity
GO:0042803 ISS protein homodimerization activity
GO:0043065 ISS positive regulation of apoptotic process
GO:0043392 ISS negative regulation of DNA binding
GO:0051354 ISS negative regulation of oxidoreductase activity
GO:0051603 ISS proteolysis involved in cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000145649 GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) protein_coding Homo_sapiens

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