C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MX dynamin-like GTPase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023341 Mx2 10090 + 16:97535308-97560900 polymorphic_pseudogene
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024112 Mx2-201 97536083-97560899 protein_coding
  ENSMUST00000188251 Mx2-001 97536081-97560900 polymorphic_pseudogene
  ENSMUST00000190097 Mx2-003 97550387-97551970 processed_transcript
  ENSMUST00000190447 Mx2-002 97535308-97560339 polymorphic_pseudogene
  ENSMUST00000191103 Mx2-004 97558412-97560518 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024112ENSMUST00000188251ENSMUST00000190097ENSMUST00000190447ENSMUST00000191103
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024112 0.668±0.00 0.139±0.05 N/A 1.799±0.00 0.441±0.08 0.108±0.02 0.107±0.00 0.162±0.07 0.776±0.29 0.279±0.07 0.107±0.05 0.407±0.17 N/A 0.254±0.23
ENSMUST00000188251 0.531±0.00 0.133±0.05 0.707±0.00 0.062±0.01 0.422±0.08 0.106±0.02 0.208±0.11 0.118±0.03 0.661±0.61 0.191±0.03 0.113±0.04 0.544±0.31 0.819±0.36 0.114±0.04
ENSMUST00000190097 N/A 0.558±0.21 N/A N/A 1.575±0.00 N/A N/A 0.261±0.03 N/A N/A 0.128±0.00 1.139±0.47 N/A 0.277±0.00
ENSMUST00000190447 N/A N/A N/A N/A N/A 0.193±0.13 0.109±0.01 N/A 0.222±0.20 N/A 0.053±0.01 0.267±0.06 N/A 0.327±0.22
ENSMUST00000191103 0.918±0.00 0.867±0.47 N/A N/A 1.152±0.50 0.555±0.25 0.409±0.00 0.487±0.02 N/A N/A 0.190±0.04 0.919±0.34 0.996±0.00 0.945±0.54

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 TAS GTPase activity
GO:0005515 IEA protein binding
GO:0005525 TAS GTP binding
GO:0005737 TAS cytoplasm
GO:0005829 IEA cytosol
GO:0006184 IEA GTP catabolic process
GO:0009615 IDA response to virus
GO:0034340 IDA response to type I interferon
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 TAS innate immune response
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051607 IEA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004953 mxb myxovirus (influenza) resistance B protein_coding Danio_rerio
ENSDARG00000008019 mxg myxovirus (influenza virus) resistance G protein_coding Danio_rerio
ENSDARG00000021688 mxa myxovirus (influenza) resistance A protein_coding Danio_rerio
ENSDARG00000023369 mxd myxovirus (influenza virus) resistance D protein_coding Danio_rerio
ENSDARG00000026049 mxf myxovirus (influenza virus) resistance F protein_coding Danio_rerio
ENSDARG00000051795 si:dkeyp-110c12.3 si:dkeyp-110c12.3 protein_coding Danio_rerio
ENSDARG00000087845 mxb myxovirus (influenza) resistance B protein_coding Danio_rerio
ENSG00000157601 MX1 MX dynamin-like GTPase 1 protein_coding Homo_sapiens

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