C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MX dynamin-like GTPase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157601 MX1 9606 + 21:41420304-41459214 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000288383 MX1-003 41431714-41459214 protein_coding
  ENST00000398598 MX1-002 41426167-41459214 protein_coding
  ENST00000398600 MX1-001 41420515-41459214 protein_coding
  ENST00000413778 MX1-007 41421329-41435935 protein_coding
  ENST00000417963 MX1-010 41426205-41440899 protein_coding
  ENST00000419044 MX1-008 41426031-41432147 protein_coding
  ENST00000424365 MX1-009 41426178-41439848 protein_coding
  ENST00000427464 MX1-013 41429481-41432175 protein_coding
  ENST00000441677 MX1-012 41426241-41435964 protein_coding
  ENST00000455164 MX1-201 41426031-41459213 protein_coding
  ENST00000467510 MX1-014 41443479-41445486 retained_intron
  ENST00000468506 MX1-006 41420366-41423277 retained_intron
  ENST00000478268 MX1-004 41426270-41429921 retained_intron
  ENST00000484465 MX1-011 41426192-41428070 retained_intron
  ENST00000486275 MX1-015 41445470-41449785 retained_intron
  ENST00000490220 MX1-005 41420304-41427866 processed_transcript
  ENST00000491110 MX1-016 41450928-41452820 retained_intron
  ENST00000619682 MX1-202 41432050-41459213 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000288383ENST00000398598ENST00000417963ENST00000455164ENST00000619682
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000288383 N/A N/A N/A N/A 4.701±0.00 1.587±0.00 N/A 1.463±0.00 0.932±0.00 3.010±0.00 N/A N/A N/A N/A
ENST00000398598 3.692±0.00 7.164±0.00 N/A 3.935±0.79 5.481±0.81 2.660±1.18 4.601±1.35 4.696±0.47 0.761±0.01 9.711±2.55 1.765±0.26 24.821±7.93 27.926±8.30 5.626±1.63
ENST00000417963 N/A N/A 1.695±0.00 3.099±0.00 9.017±0.00 N/A N/A 5.337±0.00 4.606±0.00 12.999±0.00 N/A 11.207±0.00 N/A N/A
ENST00000455164 6.140±0.00 11.137±0.00 N/A 4.924±3.54 6.687±0.00 4.905±0.00 N/A 4.388±0.00 3.369±0.00 6.972±0.00 0.535±0.00 4.761±0.00 N/A 5.503±3.02
ENST00000619682 N/A N/A N/A 4.257±0.00 4.558±0.00 2.088±0.00 1.641±0.00 N/A 1.833±0.00 N/A 1.234±0.00 N/A N/A 4.827±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CV CIL_0001CV_0004 CGP 21:41361943-41459214

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IDA cytosol
GO:0006184 IEA GTP catabolic process
GO:0006915 TAS apoptotic process
GO:0006952 TAS defense response
GO:0007165 TAS signal transduction
GO:0009615 IMP response to virus
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0034340 TAS response to type I interferon
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 TAS innate immune response
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004953 mxb myxovirus (influenza) resistance B protein_coding Danio_rerio
ENSDARG00000008019 mxg myxovirus (influenza virus) resistance G protein_coding Danio_rerio
ENSDARG00000021688 mxa myxovirus (influenza) resistance A protein_coding Danio_rerio
ENSDARG00000023369 mxd myxovirus (influenza virus) resistance D protein_coding Danio_rerio
ENSDARG00000026049 mxf myxovirus (influenza virus) resistance F protein_coding Danio_rerio
ENSDARG00000051795 si:dkeyp-110c12.3 si:dkeyp-110c12.3 protein_coding Danio_rerio
ENSDARG00000087845 mxb myxovirus (influenza) resistance B protein_coding Danio_rerio
ENSMUSG00000023341 Mx2 MX dynamin-like GTPase 2 polymorphic_pseudogene Mus_musculus

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