C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light chain 12A, regulatory, non-sarcomeric
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024048 Myl12a 10090 - 17:70993656-71002878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024846 Myl12a-006 70994294-70998012 protein_coding
  ENSMUST00000123686 Myl12a-003 70994549-71002878 protein_coding
  ENSMUST00000126529 Myl12a-002 70994294-71002165 retained_intron
  ENSMUST00000128179 Myl12a-005 70996706-71002017 protein_coding
  ENSMUST00000129093 Myl12a-007 70996385-71002160 retained_intron
  ENSMUST00000148960 Myl12a-001 70993656-71002554 protein_coding
  ENSMUST00000150456 Myl12a-004 70996134-71002187 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024846ENSMUST00000123686ENSMUST00000126529ENSMUST00000129093ENSMUST00000148960
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024846 130.088±39.35 40.916±8.36 171.221±39.26 25.884±16.75 62.784±23.38 24.377±7.39 331.978±72.69 71.126±19.79 42.461±33.87 171.415±22.69 136.541±35.50 77.519±60.30 307.416±126.07 8.570±4.64
ENSMUST00000123686 N/A 17.858±6.16 N/A 9.520±0.00 26.058±3.52 29.391±13.53 N/A 32.970±7.48 N/A N/A N/A 56.472±12.79 140.893±41.46 N/A
ENSMUST00000126529 N/A 6.510±0.00 N/A N/A 12.964±0.00 15.825±7.19 N/A N/A 3.774±0.43 N/A N/A 30.354±8.96 N/A N/A
ENSMUST00000129093 128.531±14.06 N/A N/A 15.219±0.00 42.300±3.55 N/A 153.071±36.34 83.606±6.99 N/A 221.508±15.33 N/A N/A 187.115±12.90 13.673±1.47
ENSMUST00000148960 44.985±8.55 8.107±1.39 N/A 7.436±4.62 20.253±7.56 24.506±5.87 21.704±0.00 27.150±2.93 16.925±16.84 63.277±9.02 15.209±2.95 41.542±25.40 33.271±5.38 6.106±3.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KY CIL_0006KY_0002 CGP 17:70993656-71126856

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IDA stress fiber
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0008360 IMP regulation of cell shape
GO:0016460 IDA myosin II complex
GO:0030018 IDA Z disc
GO:0035254 IPI glutamate receptor binding
GO:0043234 IEA protein complex
GO:0070062 IEA extracellular vesicular exosome
GO:0070527 IEA platelet aggregation
GO:0072661 IMP protein targeting to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014433 myl12.1 myosin, light chain 12, genome duplicate 1 protein_coding Danio_rerio
ENSDARG00000025326 myl12.2 myosin, light chain 12, genome duplicate 2 protein_coding Danio_rerio
ENSG00000101608 MYL12A myosin, light chain 12A, regulatory, non-sarcomeric protein_coding Homo_sapiens

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