C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: xanthine dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024066 Xdh 10090 - 17:73883908-73950182 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024866 Xdh-201 73883908-73950182 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024866
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024866 38.480±16.37 42.038±9.11 16.390±3.04 0.226±0.25 25.716±0.65 10.346±1.01 11.435±1.97 6.444±0.31 11.992±10.95 45.869±9.52 5.993±1.62 8.801±3.97 6.564±2.42 0.567±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VD CIL_0000VD_0002 CGP 17:73804841-73950182
CIL_0000VC CIL_0000VC_0002 CGP 17:73883908-74047916

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0004854 ISS xanthine dehydrogenase activity
GO:0004855 ISS xanthine oxidase activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005777 IEA peroxisome
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007595 IMP lactation
GO:0008762 IEA UDP-N-acetylmuramate dehydrogenase activity
GO:0009055 IEA electron carrier activity
GO:0009115 ISS xanthine catabolic process
GO:0010629 IEA negative regulation of gene expression
GO:0016491 IDA oxidoreductase activity
GO:0030151 IEA molybdenum ion binding
GO:0030856 IMP regulation of epithelial cell differentiation
GO:0042803 IEA protein homodimerization activity
GO:0043546 ISS molybdopterin cofactor binding
GO:0045602 IEA negative regulation of endothelial cell differentiation
GO:0050660 ISS flavin adenine dinucleotide binding
GO:0051537 ISS 2 iron, 2 sulfur cluster binding
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0055114 IDA oxidation-reduction process
GO:1900745 IEA positive regulation of p38MAPK cascade
GO:1900747 IEA negative regulation of vascular endothelial growth factor signaling pathway
GO:2000379 IEA positive regulation of reactive oxygen species metabolic process
GO:2001213 IEA negative regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055240 xdh xanthine dehydrogenase protein_coding Danio_rerio
ENSG00000158125 XDH xanthine dehydrogenase protein_coding Homo_sapiens

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