C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ferrochelatase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024588 Fech 10090 - 18:64456550-64489066 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025484 Fech-201 64456550-64489066 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025484
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025484 27.023±1.51 55.514±12.66 8.579±0.68 5.070±1.67 23.315±2.99 15.576±0.98 38.311±7.97 38.386±2.06 130.089±94.68 18.316±0.44 46.443±2.37 23.328±4.88 16.776±12.03 7.634±2.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006O8 CIL_0006O8_0002 CGP 18:64340364-64489066
CIL_0006O9 CIL_0006O9_0002 CGP 18:64456550-64516557

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004325 IDA ferrochelatase activity
GO:0005506 IDA iron ion binding
GO:0005515 IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006779 IMP porphyrin-containing compound biosynthetic process
GO:0006783 TAS heme biosynthetic process
GO:0008203 IMP cholesterol metabolic process
GO:0009416 IMP response to light stimulus
GO:0009589 IMP detection of UV
GO:0010038 IEA response to metal ion
GO:0010288 IEA response to lead ion
GO:0010468 IMP regulation of gene expression
GO:0010999 IGI regulation of eIF2 alpha phosphorylation by heme
GO:0017085 IEA response to insecticide
GO:0020037 IDA heme binding
GO:0030218 IMP erythrocyte differentiation
GO:0030350 IDA iron-responsive element binding
GO:0034379 IMP very-low-density lipoprotein particle assembly
GO:0042493 IEA response to drug
GO:0045471 IEA response to ethanol
GO:0046501 IGI protoporphyrinogen IX metabolic process
GO:0046685 IEA response to arsenic-containing substance
GO:0046906 IDA tetrapyrrole binding
GO:0046984 IGI regulation of hemoglobin biosynthetic process
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0051597 IEA response to methylmercury
GO:0055072 IMP iron ion homeostasis
GO:0070541 IEA response to platinum ion
GO:0071549 IEA cellular response to dexamethasone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003462 fech ferrochelatase protein_coding Danio_rerio
ENSG00000066926 FECH ferrochelatase protein_coding Homo_sapiens

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