C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet derived growth factor receptor, beta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024620 Pdgfrb 10090 + 18:61045150-61085061 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025522 Pdgfrb-001 61045150-61085061 protein_coding
  ENSMUST00000115274 Pdgfrb-002 61045200-61085056 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025522ENSMUST00000115274
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025522 32.489±5.36 15.594±1.43 15.255±2.94 7.084±2.26 25.191±4.31 10.955±1.50 19.111±0.54 18.936±3.90 2.252±0.75 46.212±9.28 4.311±1.32 32.433±8.96 19.398±13.08 0.676±0.36
ENSMUST00000115274 N/A N/A N/A N/A N/A 1.197±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091Q CIL_00091Q_0002 VISTA 18:60604549-61207221
CIL_00079E CIL_00079E_0002 CGP 18:61018862-61085061

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001822 IMP kidney development
GO:0001894 IMP tissue homeostasis
GO:0004871 IDA signal transducer activity
GO:0005019 IEA platelet-derived growth factor beta-receptor activity
GO:0005102 IEA receptor binding
GO:0005161 IEA platelet-derived growth factor receptor binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006024 IEA glycosaminoglycan biosynthetic process
GO:0006807 IMP nitrogen compound metabolic process
GO:0007165 IDA signal transduction
GO:0008284 IEA positive regulation of cell proliferation
GO:0009636 IEA response to toxic substance
GO:0009986 IDA cell surface
GO:0010863 IEA positive regulation of phospholipase C activity
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016301 IMP kinase activity
GO:0016324 IEA apical plasma membrane
GO:0016477 IEA cell migration
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030325 IGI adrenal gland development
GO:0030335 IEA positive regulation of cell migration
GO:0031226 IEA intrinsic component of plasma membrane
GO:0032355 IEA response to estradiol
GO:0032516 IEA positive regulation of phosphoprotein phosphatase activity
GO:0032526 IEA response to retinoic acid
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0033993 IEA response to lipid
GO:0034405 IEA response to fluid shear stress
GO:0035556 IEA intracellular signal transduction
GO:0035789 IEA metanephric mesenchymal cell migration
GO:0035791 IEA platelet-derived growth factor receptor-beta signaling pathway
GO:0038085 IEA vascular endothelial growth factor binding
GO:0038091 IEA positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
GO:0042060 IEA wound healing
GO:0042542 IEA response to hydrogen peroxide
GO:0043066 IEA negative regulation of apoptotic process
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0043552 IEA positive regulation of phosphatidylinositol 3-kinase activity
GO:0043627 IEA response to estrogen
GO:0046488 IEA phosphatidylinositol metabolic process
GO:0046777 IEA protein autophosphorylation
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0048407 IEA platelet-derived growth factor binding
GO:0048705 IMP skeletal system morphogenesis
GO:0048745 IMP smooth muscle tissue development
GO:0048839 IEA inner ear development
GO:0050730 IMP regulation of peptidyl-tyrosine phosphorylation
GO:0055093 IEA response to hyperoxia
GO:0060326 IEA cell chemotaxis
GO:0070062 IEA extracellular vesicular exosome
GO:0072075 IEA metanephric mesenchyme development
GO:0072275 IEA metanephric glomerulus morphogenesis
GO:0072278 IEA metanephric comma-shaped body morphogenesis
GO:0072284 IEA metanephric S-shaped body morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057345 pdgfrb platelet derived growth factor receptor beta protein_coding Danio_rerio
ENSG00000113721 PDGFRB platelet-derived growth factor receptor, beta polypeptide protein_coding Homo_sapiens

Loading