C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proprotein convertase subtilisin/kexin type 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024713 Pcsk5 10090 - 19:17432832-17837632 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025618 Pcsk5-201 17432832-17837632 protein_coding
  ENSMUST00000050715 Pcsk5-202 17558159-17837632 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025618ENSMUST00000050715
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025618 N/A 14.471±5.42 N/A N/A N/A 4.139±1.32 0.065±0.00 2.269±0.88 0.815±0.56 N/A N/A 2.054±0.86 0.381±0.12 0.062±0.02
ENSMUST00000050715 3.990±2.75 8.064±2.93 2.343±0.11 1.464±0.41 2.664±0.75 N/A 0.511±0.15 0.656±0.09 0.311±0.08 5.760±0.45 0.198±0.05 6.693±2.99 0.973±1.40 0.242±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002001 IEA renin secretion into blood stream
GO:0004175 IDA endopeptidase activity
GO:0004252 IDA serine-type endopeptidase activity
GO:0005615 IDA extracellular space
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005794 IDA Golgi apparatus
GO:0006465 IEA signal peptide processing
GO:0006508 IEA proteolysis
GO:0007507 IMP heart development
GO:0007566 IMP embryo implantation
GO:0008233 ISO peptidase activity
GO:0009952 IMP anterior/posterior pattern specification
GO:0016021 IEA integral component of membrane
GO:0016485 ISO protein processing
GO:0016486 IDA peptide hormone processing
GO:0019058 IDA viral life cycle
GO:0030141 IDA secretory granule
GO:0030323 IMP respiratory tube development
GO:0035108 IMP limb morphogenesis
GO:0042089 IDA cytokine biosynthetic process
GO:0042277 IDA peptide binding
GO:0043043 IDA peptide biosynthetic process
GO:0048566 IMP embryonic digestive tract development
GO:0048706 IMP embryonic skeletal system development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060518 pcsk5b proprotein convertase subtilisin/kexin type 5b protein_coding Danio_rerio
ENSDARG00000074659 FP236851.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000099139 PCSK5 proprotein convertase subtilisin/kexin type 5 protein_coding Homo_sapiens

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