C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025618 Pcsk5-201 ENSMUSG00000024713 10090 - 19:17432832-17837632 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonHeartKidneyLiverOvaryPlacentaTestisENSMUST00000025618
Transcript ID Adrenal Colon Heart Kidney Liver Ovary Placenta Testis
ENSMUST00000025618 14.471±5.42 4.139±1.32 0.065±0.00 2.269±0.88 0.815±0.56 2.054±0.86 0.381±0.12 0.062±0.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002001 IEA renin secretion into blood stream
GO:0004175 IDA endopeptidase activity
GO:0004252 IDA serine-type endopeptidase activity
GO:0005615 IDA extracellular space
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005794 IDA Golgi apparatus
GO:0006465 IEA signal peptide processing
GO:0006508 IEA proteolysis
GO:0007507 IMP heart development
GO:0007566 IMP embryo implantation
GO:0008233 ISO peptidase activity
GO:0009952 IMP anterior/posterior pattern specification
GO:0016021 IEA integral component of membrane
GO:0016485 ISO protein processing
GO:0016486 IDA peptide hormone processing
GO:0019058 IDA viral life cycle
GO:0030141 IDA secretory granule
GO:0030323 IMP respiratory tube development
GO:0035108 IMP limb morphogenesis
GO:0042089 IDA cytokine biosynthetic process
GO:0042277 IDA peptide binding
GO:0043043 IDA peptide biosynthetic process
GO:0048566 IMP embryonic digestive tract development
GO:0048706 IMP embryonic skeletal system development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000376752 PCSK5-001 protein_coding Homo_sapiens 0 3290
ENST00000376767 PCSK5-003 protein_coding Homo_sapiens 0 2567
ENST00000424854 PCSK5-002 protein_coding Homo_sapiens 0 3825
ENST00000545128 PCSK5-201 protein_coding Homo_sapiens 0 3956

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