C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysosomal acid lipase A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024781 Lipa 10090 - 19:34492318-34527474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049572 Lipa-201 34492318-34527474 protein_coding
  ENSMUST00000178114 Lipa-202 34492318-34527474 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049572ENSMUST00000178114
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049572 26.109±2.50 68.356±13.50 14.354±0.66 5.039±2.47 28.057±4.65 14.384±3.35 9.449±0.72 119.956±7.60 65.287±39.38 31.348±1.82 1.560±0.51 21.270±4.86 10.880±6.78 1.708±0.75
ENSMUST00000178114 3.328±0.23 9.867±2.65 1.896±0.01 0.505±0.20 4.363±1.11 N/A 1.189±0.00 14.996±0.60 8.456±4.81 3.958±0.14 0.721±0.19 4.138±0.00 2.424±1.43 0.221±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IW CIL_0001IW_0002 CGP 19:34473786-34527474
CIL_0001IT CIL_0001IT_0002 CGP 19:34492318-34576419

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0001816 IMP cytokine production
GO:0004771 IEA sterol esterase activity
GO:0005764 IEA lysosome
GO:0006954 IMP inflammatory response
GO:0008283 IMP cell proliferation
GO:0016042 IEA lipid catabolic process
GO:0016298 IEA lipase activity
GO:0030324 IMP lung development
GO:0048771 IMP tissue remodeling
GO:0048873 IMP homeostasis of number of cells within a tissue
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018529 lipf lipase, gastric protein_coding Danio_rerio
ENSG00000107798 LIPA lipase A, lysosomal acid, cholesterol esterase protein_coding Homo_sapiens

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