C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fatty acid synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025153 Fasn 10090 - 11:120805940-120824178 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055655 Fasn-001 120805940-120824178 protein_coding
  ENSMUST00000146541 Fasn-002 120808564-120809701 retained_intron
  ENSMUST00000155276 Fasn-003 120807547-120808600 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055655ENSMUST00000146541ENSMUST00000155276
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055655 897.038±37.16 809.529±109.18 15.024±4.41 25.901±4.57 1484.457±568.51 39.993±3.55 39.738±15.77 93.455±31.04 33.491±28.20 148.597±24.22 2.071±0.65 116.934±50.90 9.619±5.71 7.065±2.69
ENSMUST00000146541 N/A N/A N/A 69.087±0.00 3276.620±0.00 N/A N/A N/A N/A N/A N/A 67.854±0.00 31.236±18.84 N/A
ENSMUST00000155276 1931.230±45.69 N/A 41.910±0.00 N/A N/A N/A N/A 199.605±0.00 112.043±17.08 N/A N/A 216.953±55.34 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004VI CIL_0004VI_0002 CGP 11:120789201-120824178
CIL_00043S CIL_00043S_0003 CGP 11:120805940-120932872

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0004312 IEA fatty acid synthase activity
GO:0004313 IEA [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 IEA [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315 IEA 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 IEA 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004317 IEA 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004319 IEA enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004320 IEA oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006084 IEA acetyl-CoA metabolic process
GO:0006633 IEA fatty acid biosynthetic process
GO:0008144 IEA drug binding
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0016295 IEA myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 IEA palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0042587 IDA glycogen granule
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0044822 IEA poly(A) RNA binding
GO:0047117 IEA enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
GO:0047451 IEA 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome
GO:0070402 IEA NADPH binding
GO:0071353 IDA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078895 fasn fatty acid synthase protein_coding Danio_rerio
ENSDARG00000087657 fasn fatty acid synthase protein_coding Danio_rerio
ENSG00000169710 FASN fatty acid synthase protein_coding Homo_sapiens

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