C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025194 Abcc2 10090 + 19:43782192-43840740 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026208 Abcc2-001 43782192-43840740 protein_coding
  ENSMUST00000099413 Abcc2-201 43838803-43840728 protein_coding
  ENSMUST00000129943 Abcc2-003 43797986-43800769 retained_intron
  ENSMUST00000143553 Abcc2-002 43782326-43784640 retained_intron
  ENSMUST00000146737 Abcc2-004 43810522-43813401 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026208ENSMUST00000099413ENSMUST00000129943ENSMUST00000143553
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026208 0.083±0.02 0.054±0.02 0.006±0.00 0.135±0.10 0.136±0.05 0.009±0.00 36.437±1.27 42.390±33.88 0.026±0.01 0.005±0.00 0.260±0.16 3.720±4.19 0.083±0.03
ENSMUST00000099413 N/A 0.057±0.02 0.034±0.00 0.144±0.02 0.193±0.00 0.022±0.01 N/A N/A 0.041±0.02 0.015±0.00 0.275±0.00 N/A 0.102±0.00
ENSMUST00000129943 N/A 0.189±0.06 0.041±0.00 N/A N/A N/A N/A N/A N/A N/A 0.637±0.00 N/A N/A
ENSMUST00000143553 N/A N/A N/A N/A N/A 0.078±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EZ CIL_0000EZ_0002 CGP 19:43752996-43840740
CIL_00054Q CIL_00054Q_0002 CGP 19:43782192-43912392

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006855 IEA drug transmembrane transport
GO:0006979 IEA response to oxidative stress
GO:0009408 IEA response to heat
GO:0009986 IEA cell surface
GO:0015732 IEA prostaglandin transport
GO:0016020 IDA membrane
GO:0016324 IDA apical plasma membrane
GO:0019904 IEA protein domain specific binding
GO:0030644 IEA cellular chloride ion homeostasis
GO:0031427 IEA response to methotrexate
GO:0042493 IEA response to drug
GO:0042626 IEA ATPase activity, coupled to transmembrane movement of substances
GO:0043627 IEA response to estrogen
GO:0046581 IDA intercellular canaliculus
GO:0046685 IEA response to arsenic-containing substance
GO:0070327 IEA thyroid hormone transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014031 abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 protein_coding Danio_rerio
ENSG00000023839 ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 protein_coding Homo_sapiens

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