C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, J
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025314 Ptprj 10090 - 2:90429754-90580647 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000111493 Ptprj-001 90432889-90471336 protein_coding
  ENSMUST00000111495 Ptprj-002 90429756-90479170 protein_coding
  ENSMUST00000129323 Ptprj-003 90429754-90430445 processed_transcript
  ENSMUST00000168621 Ptprj-201 90432889-90580647 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000111493ENSMUST00000111495ENSMUST00000168621
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000111493 1.201±0.15 N/A 2.345±0.28 4.012±2.87 5.170±3.28 N/A 0.723±0.30 N/A 1.774±0.42 N/A 0.421±0.15 3.454±0.93 1.991±0.71 2.452±0.28
ENSMUST00000111495 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.262±0.56
ENSMUST00000168621 4.552±2.99 2.186±0.52 1.324±0.20 2.122±0.96 6.965±2.08 15.110±2.10 0.723±0.17 11.454±0.60 5.083±3.96 9.354±0.88 0.185±0.06 2.661±0.52 1.291±0.57 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IMP vasculogenesis
GO:0001772 IDA immunological synapse
GO:0001954 IDA positive regulation of cell-matrix adhesion
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005161 IEA platelet-derived growth factor receptor binding
GO:0005886 IDA plasma membrane
GO:0005911 ISS cell-cell junction
GO:0007507 IMP heart development
GO:0007596 IMP blood coagulation
GO:0008013 IEA beta-catenin binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010572 IMP positive regulation of platelet activation
GO:0010642 IDA negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010759 IDA positive regulation of macrophage chemotaxis
GO:0016021 IEA integral component of membrane
GO:0016791 ISS phosphatase activity
GO:0019901 IEA protein kinase binding
GO:0030155 IEA regulation of cell adhesion
GO:0030308 IEA negative regulation of cell growth
GO:0030336 IDA negative regulation of cell migration
GO:0032587 IDA ruffle membrane
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042059 ISS negative regulation of epidermal growth factor receptor signaling pathway
GO:0043116 IEA negative regulation of vascular permeability
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0045295 IEA gamma-catenin binding
GO:0045785 IEA positive regulation of cell adhesion
GO:0048008 ISS platelet-derived growth factor receptor signaling pathway
GO:0048709 IMP oligodendrocyte differentiation
GO:0050860 IDA negative regulation of T cell receptor signaling pathway
GO:0050918 IEA positive chemotaxis
GO:0051019 IEA mitogen-activated protein kinase binding
GO:0051894 ISS positive regulation of focal adhesion assembly
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0070062 IEA extracellular vesicular exosome
GO:0070097 IEA delta-catenin binding
GO:2000272 IMP negative regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033042 ptprja protein tyrosine phosphatase, receptor type, J a protein_coding Danio_rerio
ENSDARG00000086511 PTPRJ (2 of 3) protein tyrosine phosphatase, receptor type, J protein_coding Danio_rerio
ENSDARG00000091539 ptprjb protein tyrosine phosphatase, receptor type, J b protein_coding Danio_rerio
ENSG00000149177 PTPRJ protein tyrosine phosphatase, receptor type, J protein_coding Homo_sapiens

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