C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, J
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149177 PTPRJ 9606 + 11:47980558-48170841 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000418331 PTPRJ-001 47980561-48168118 protein_coding
  ENST00000440289 PTPRJ-002 47980580-48132720 protein_coding
  ENST00000526550 PTPRJ-004 48044804-48121147 processed_transcript
  ENST00000527026 PTPRJ-005 48145078-48149866 retained_intron
  ENST00000527952 PTPRJ-003 47980727-48123700 protein_coding
  ENST00000534219 PTPRJ-006 47980727-48121247 protein_coding
  ENST00000613246 PTPRJ-201 47980558-48170841 protein_coding
  ENST00000615445 PTPRJ-202 47980569-48167762 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000418331ENST00000440289ENST00000526550ENST00000613246
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000418331 N/A 4.955±0.00 3.082±0.00 4.002±0.00 2.166±0.00 0.632±0.00 6.016±0.00 2.080±0.00 3.647±0.00 4.451±0.00 N/A N/A
ENST00000440289 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.222±0.00
ENST00000526550 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.393±0.00
ENST00000613246 2.345±0.00 N/A 1.573±0.00 N/A 0.670±0.00 1.317±0.00 N/A N/A 1.297±0.00 1.291±0.75 3.806±0.00 0.326±0.01

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IEA vasculogenesis
GO:0001772 IDA immunological synapse
GO:0001954 IEA positive regulation of cell-matrix adhesion
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005161 IPI platelet-derived growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006470 IEA protein dephosphorylation
GO:0007507 IEA heart development
GO:0007596 IEA blood coagulation
GO:0008013 IPI beta-catenin binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010572 IEA positive regulation of platelet activation
GO:0010642 IDA negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010759 IEA positive regulation of macrophage chemotaxis
GO:0016311 IEA dephosphorylation
GO:0016791 IMP:IEA phosphatase activity
GO:0019901 IPI protein kinase binding
GO:0030155 IMP regulation of cell adhesion
GO:0030308 IDA negative regulation of cell growth
GO:0030336 IDA negative regulation of cell migration
GO:0032587 IEA ruffle membrane
GO:0035335 IDA peptidyl-tyrosine dephosphorylation
GO:0042059 IMP negative regulation of epidermal growth factor receptor signaling pathway
GO:0042995 IEA cell projection
GO:0043116 IDA negative regulation of vascular permeability
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0045295 IPI gamma-catenin binding
GO:0045785 IMP positive regulation of cell adhesion
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048709 IEA oligodendrocyte differentiation
GO:0050860 IMP negative regulation of T cell receptor signaling pathway
GO:0050918 IDA positive chemotaxis
GO:0051019 IPI mitogen-activated protein kinase binding
GO:0051894 IMP positive regulation of focal adhesion assembly
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060242 NAS contact inhibition
GO:0070062 IDA extracellular vesicular exosome
GO:0070097 IPI delta-catenin binding
GO:2000272 IEA negative regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033042 ptprja protein tyrosine phosphatase, receptor type, J a protein_coding Danio_rerio
ENSDARG00000086511 PTPRJ (2 of 3) protein tyrosine phosphatase, receptor type, J protein_coding Danio_rerio
ENSDARG00000091539 ptprjb protein tyrosine phosphatase, receptor type, J b protein_coding Danio_rerio
ENSMUSG00000025314 Ptprj protein tyrosine phosphatase, receptor type, J protein_coding Mus_musculus

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