C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin beta 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025321 Itgb8 10090 - 12:119158022-119238802 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026360 Itgb8-001 119158022-119238802 protein_coding
  ENSMUST00000137804 Itgb8-002 119201463-119238770 retained_intron
  ENSMUST00000151023 Itgb8-003 119188106-119238801 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026360ENSMUST00000137804ENSMUST00000151023
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026360 0.720±0.65 0.523±0.24 0.460±0.00 3.113±0.23 0.532±0.16 0.185±0.09 0.274±0.02 11.726±0.64 0.021±0.01 0.317±0.07 0.097±0.02 0.483±0.23 0.119±0.14 0.038±0.02
ENSMUST00000137804 N/A N/A N/A N/A N/A 0.145±0.00 N/A N/A N/A 0.201±0.00 N/A 0.591±0.28 N/A 0.035±0.01
ENSMUST00000151023 0.034±0.00 0.438±0.25 N/A N/A N/A 0.141±0.00 N/A N/A N/A N/A N/A 0.685±0.49 N/A 0.043±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001573 IMP ganglioside metabolic process
GO:0004872 IEA receptor activity
GO:0005102 IEA receptor binding
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 IEA integrin complex
GO:0009986 IEA cell surface
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0034686 IEA integrin alphav-beta8 complex
GO:0051216 IEA cartilage development
GO:0070062 IEA extracellular vesicular exosome
GO:1990430 IEA extracellular matrix protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028222 itgb8 integrin, beta 8 protein_coding Danio_rerio
ENSG00000105855 ITGB8 integrin, beta 8 protein_coding Homo_sapiens

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