C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025494 Sigirr 10090 - 7:141091175-141100546 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097958 Sigirr-201 141091175-141100546 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097958
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097958 2.066±0.75 0.861±0.22 1.916±0.00 0.206±0.15 4.933±1.59 5.565±1.76 1.109±0.70 16.405±7.59 8.088±5.92 5.594±1.52 0.783±0.11 1.235±0.84 3.141±2.69 0.573±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002AQ CIL_0002AQ_0002 CGP 7:141078218-141100546
CIL_0002UO CIL_0002UO_0002 CGP 7:141091175-141117806

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001960 IMP negative regulation of cytokine-mediated signaling pathway
GO:0006953 IMP acute-phase response
GO:0007165 IEA signal transduction
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0043433 ISS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045079 IMP negative regulation of chemokine biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062204 sigirr single immunoglobulin and toll-interleukin 1 receptor (TIR) domain protein_coding Danio_rerio
ENSG00000185187 SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain protein_coding Homo_sapiens

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