C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPS8-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025504 Eps8l2 10090 + 7:141338880-141363020 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026577 Eps8l2-001 141338880-141363020 protein_coding
  ENSMUST00000127501 Eps8l2-010 141357996-141361415 retained_intron
  ENSMUST00000133669 Eps8l2-007 141360246-141361732 processed_transcript
  ENSMUST00000136240 Eps8l2-008 141358203-141361734 processed_transcript
  ENSMUST00000136736 Eps8l2-004 141339004-141355792 retained_intron
  ENSMUST00000140025 Eps8l2-002 141338956-141363020 retained_intron
  ENSMUST00000143633 Eps8l2-003 141339006-141342990 protein_coding
  ENSMUST00000145108 Eps8l2-006 141338987-141355794 processed_transcript
  ENSMUST00000146042 Eps8l2-005 141342656-141355929 retained_intron
  ENSMUST00000155729 Eps8l2-009 141361537-141362667 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026577ENSMUST00000140025ENSMUST00000145108
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026577 2.079±0.26 0.422±0.18 8.703±1.67 0.172±0.06 3.759±0.43 33.579±2.90 0.627±0.27 25.146±2.62 7.402±3.94 10.789±3.23 0.300±0.10 2.161±0.47 79.462±56.82 0.676±0.31
ENSMUST00000140025 1.464±0.33 0.410±0.16 9.400±2.27 0.113±0.02 2.883±0.97 33.366±4.83 0.337±0.09 12.338±4.41 4.667±2.55 9.092±0.31 0.192±0.00 1.797±0.47 17.747±7.78 N/A
ENSMUST00000145108 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.334±0.50 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISO ruffle
GO:0003779 IEA actin binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007266 IEA Rho protein signal transduction
GO:0016601 ISO Rac protein signal transduction
GO:0030676 IEA Rac guanyl-nucleotide exchange factor activity
GO:0031982 IEA vesicle
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032587 IEA ruffle membrane
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043234 IEA protein complex
GO:0051015 ISO actin filament binding
GO:0070062 IEA extracellular vesicular exosome
GO:1900029 IEA positive regulation of ruffle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058108 EPS8L2 (1 of 2) EPS8-like 2 protein_coding Danio_rerio
ENSDARG00000069011 EPS8L2 (2 of 2) EPS8-like 2 protein_coding Danio_rerio
ENSG00000177106 EPS8L2 EPS8-like 2 protein_coding Homo_sapiens

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