C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPS8-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177106 EPS8L2 9606 + 11:694438-727727 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318562 EPS8L2-001 706113-727727 protein_coding
  ENST00000524474 EPS8L2-028 720606-722584 retained_intron
  ENST00000524763 EPS8L2-008 694438-720212 protein_coding
  ENST00000524973 EPS8L2-035 726954-727658 processed_transcript
  ENST00000526198 EPS8L2-006 709368-727034 protein_coding
  ENST00000526380 EPS8L2-013 706616-709789 retained_intron
  ENST00000526651 EPS8L2-029 721019-722500 retained_intron
  ENST00000526909 EPS8L2-004 706224-727721 nonsense_mediated_decay
  ENST00000527199 EPS8L2-009 705217-709584 protein_coding
  ENST00000527807 EPS8L2-017 706242-720191 retained_intron
  ENST00000527832 EPS8L2-030 724562-727722 retained_intron
  ENST00000528770 EPS8L2-036 721075-727723 nonsense_mediated_decay
  ENST00000529346 EPS8L2-005 706203-722302 retained_intron
  ENST00000529680 EPS8L2-011 706231-709795 retained_intron
  ENST00000530093 EPS8L2-012 706231-710482 retained_intron
  ENST00000530118 EPS8L2-018 709560-720899 retained_intron
  ENST00000530452 EPS8L2-022 721085-723345 nonsense_mediated_decay
  ENST00000530636 EPS8L2-002 706629-727051 protein_coding
  ENST00000531348 EPS8L2-026 706595-720181 protein_coding
  ENST00000531393 EPS8L2-007 721926-727721 retained_intron
  ENST00000531471 EPS8L2-037 720972-721631 retained_intron
  ENST00000532545 EPS8L2-023 721073-721800 retained_intron
  ENST00000533256 EPS8L2-003 706117-727724 protein_coding
  ENST00000533500 EPS8L2-016 706237-720147 protein_coding
  ENST00000533816 EPS8L2-020 721282-722343 retained_intron
  ENST00000534027 EPS8L2-034 726561-727051 retained_intron
  ENST00000534449 EPS8L2-033 726627-727722 processed_transcript
  ENST00000534679 EPS8L2-032 726081-727113 retained_intron
  ENST00000534755 EPS8L2-027 706201-720135 protein_coding
  ENST00000610855 EPS8L2-201 721926-727048 protein_coding
  ENST00000614442 EPS8L2-202 706120-727726 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000318562ENST00000524474ENST00000526198ENST00000526909ENST00000530636ENST00000531393ENST00000533256ENST00000533500ENST00000534027
Transcript ID Bladder Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000318562 4.072±0.00 4.528±2.51 4.478±1.94 30.487±0.00 19.333±0.00 18.043±0.00 10.041±5.70 30.488±7.28 5.305±0.00
ENST00000524474 N/A N/A N/A N/A 2.471±0.00 N/A N/A N/A N/A
ENST00000526198 N/A N/A 3.423±0.00 3.152±0.00 N/A N/A 51.498±0.00 15.473±0.00 N/A
ENST00000526909 2.268±0.00 N/A N/A 0.845±0.00 N/A N/A N/A N/A N/A
ENST00000530636 3.855±0.00 N/A N/A N/A N/A N/A 2.187±0.00 N/A N/A
ENST00000531393 N/A N/A N/A N/A N/A N/A 11.988±0.00 N/A N/A
ENST00000533256 N/A N/A N/A N/A 7.739±0.00 N/A N/A N/A N/A
ENST00000533500 N/A N/A N/A 8.960±0.00 N/A N/A N/A N/A N/A
ENST00000534027 N/A N/A N/A N/A N/A N/A 229.374±0.00 77.297±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OP CIL_0003OP_0001 CGP 11:637293-706715

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IDA actin binding
GO:0005089 IDA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007266 IDA Rho protein signal transduction
GO:0030676 IDA Rac guanyl-nucleotide exchange factor activity
GO:0031982 IDA vesicle
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032587 IDA ruffle membrane
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0035023 IDA regulation of Rho protein signal transduction
GO:0043234 IDA protein complex
GO:0070062 IDA extracellular vesicular exosome
GO:1900029 IGI positive regulation of ruffle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058108 EPS8L2 (1 of 2) EPS8-like 2 protein_coding Danio_rerio
ENSDARG00000069011 EPS8L2 (2 of 2) EPS8-like 2 protein_coding Danio_rerio
ENSMUSG00000025504 Eps8l2 EPS8-like 2 protein_coding Mus_musculus

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