C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: X-linked inhibitor of apoptosis
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025860 Xiap 10090 + X:42059679-42109656 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026978 Xiap-002 42093728-42109656 protein_coding
  ENSMUST00000055483 Xiap-001 42071325-42109656 protein_coding
  ENSMUST00000115094 Xiap-003 42067836-42109656 protein_coding
  ENSMUST00000115095 Xiap-004 42068398-42109656 protein_coding
  ENSMUST00000126375 Xiap-007 42067881-42094556 protein_coding
  ENSMUST00000141316 Xiap-006 42059679-42072637 processed_transcript
  ENSMUST00000145065 Xiap-005 42068755-42109656 processed_transcript
  ENSMUST00000146874 Xiap-008 42068410-42072637 processed_transcript
  ENSMUST00000150635 Xiap-009 42067918-42104819 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026978ENSMUST00000055483ENSMUST00000115094ENSMUST00000115095ENSMUST00000126375ENSMUST00000145065
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026978 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.357±0.00 1.488±0.00 N/A N/A
ENSMUST00000055483 3.380±0.29 N/A N/A N/A N/A 2.362±0.28 0.651±0.00 1.195±0.02 3.056±1.08 4.473±0.00 N/A 3.997±1.08 2.407±0.20 N/A
ENSMUST00000115094 2.105±1.30 2.120±0.26 N/A 2.997±0.16 2.021±1.40 2.246±0.89 1.701±0.55 2.227±1.02 1.802±0.39 4.257±1.42 1.442±0.36 2.164±0.81 2.548±0.47 0.198±0.10
ENSMUST00000115095 1.074±0.22 1.129±0.24 2.007±0.04 2.059±0.20 N/A N/A 0.993±0.23 1.306±0.07 2.797±0.57 2.369±0.35 1.095±0.39 2.815±1.22 1.615±0.59 0.210±0.10
ENSMUST00000126375 N/A 4.409±1.38 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000145065 4.828±0.76 1.346±0.00 7.235±0.00 6.483±1.02 2.344±0.91 2.576±0.15 1.149±0.48 2.441±0.95 5.037±3.60 7.244±1.65 1.233±0.37 4.421±1.86 5.357±2.34 0.553±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YQ CIL_0007YQ_0002 VISTA X:42042580-42644283
CIL_0000GB CIL_0000GB_0003 CGP X:42059679-42277185

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0008270 IEA zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016874 IEA ligase activity
GO:0043066 IDA negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043234 IEA protein complex
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051402 IMP neuron apoptotic process
GO:0097110 IEA scaffold protein binding
GO:1990001 IMP inhibition of cysteine-type endopeptidase activity involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016143 xiap X-linked inhibitor of apoptosis protein_coding Danio_rerio
ENSG00000163098 BIRC8 baculoviral IAP repeat containing 8 protein_coding Homo_sapiens

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