C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serum/glucocorticoid regulated kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025915 Sgk3 10090 + 1:9798107-9900845 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097826 Sgk3-009 9848397-9899853 protein_coding
  ENSMUST00000166384 Sgk3-004 9798107-9900843 protein_coding
  ENSMUST00000168907 Sgk3-001 9798143-9900845 protein_coding
  ENSMUST00000171265 Sgk3-008 9848272-9900843 protein_coding
  ENSMUST00000188298 Sgk3-007 9798208-9900008 nonsense_mediated_decay
  ENSMUST00000188486 Sgk3-012 9895427-9899174 retained_intron
  ENSMUST00000188625 Sgk3-005 9798158-9830338 retained_intron
  ENSMUST00000188738 Sgk3-006 9798185-9899618 nonsense_mediated_decay
  ENSMUST00000188782 Sgk3-002 9798143-9900770 nonsense_mediated_decay
  ENSMUST00000188830 Sgk3-014 9848321-9865631 processed_transcript
  ENSMUST00000189050 Sgk3-013 9848321-9872554 retained_intron
  ENSMUST00000191338 Sgk3-010 9883467-9889077 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097826ENSMUST00000166384ENSMUST00000168907ENSMUST00000171265ENSMUST00000188298ENSMUST00000188486ENSMUST00000188625ENSMUST00000188738ENSMUST00000188782ENSMUST00000188830ENSMUST00000191338
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097826 0.431±0.00 N/A 1.415±0.40 0.686±0.11 1.200±0.44 N/A 1.649±0.13 1.582±0.00 6.355±4.22 1.271±0.31 0.692±0.29 1.256±0.69 8.982±4.53 1.894±0.75
ENSMUST00000166384 0.719±0.23 N/A 1.089±0.13 0.473±0.11 0.607±0.00 0.406±0.19 0.900±0.22 1.076±0.44 4.553±3.63 1.257±0.13 0.399±0.07 0.448±0.00 3.209±1.26 1.036±0.37
ENSMUST00000168907 1.976±0.95 1.229±0.31 1.958±0.20 0.393±0.16 1.975±0.75 0.384±0.24 1.193±0.07 2.587±1.14 4.862±2.26 2.779±1.21 0.741±0.18 1.173±0.58 5.880±2.85 1.507±0.37
ENSMUST00000171265 0.643±0.00 N/A 1.112±0.34 1.070±0.00 1.336±0.04 N/A 0.673±0.00 1.195±0.36 1.811±0.00 0.910±0.00 N/A 0.985±1.03 8.049±0.03 1.241±0.30
ENSMUST00000188298 N/A N/A N/A N/A N/A N/A N/A N/A 0.404±0.00 N/A 0.369±0.00 N/A N/A N/A
ENSMUST00000188486 N/A 0.292±0.14 N/A 0.270±0.00 0.533±0.16 0.100±0.02 N/A N/A N/A N/A N/A 0.374±0.14 N/A 0.454±0.00
ENSMUST00000188625 N/A N/A N/A N/A N/A 0.121±0.00 N/A N/A N/A N/A N/A 0.271±0.00 N/A N/A
ENSMUST00000188738 N/A N/A N/A 0.281±0.00 1.214±0.00 0.207±0.05 N/A N/A 0.306±0.00 N/A N/A 0.434±0.01 N/A N/A
ENSMUST00000188782 N/A N/A N/A N/A N/A 0.204±0.00 N/A N/A 0.529±0.00 N/A N/A 1.538±0.58 0.960±0.00 N/A
ENSMUST00000188830 N/A N/A N/A 6.872±0.00 N/A 0.799±0.00 N/A N/A N/A N/A N/A 8.389±0.00 58.470±25.08 16.906±0.00
ENSMUST00000191338 N/A 0.287±0.00 N/A N/A N/A 0.166±0.03 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003BG CIL_0003BG_0002 CGP 1:9718622-9900845
CIL_0003BJ CIL_0003BJ_0002 CGP 1:9798107-9942085

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005524 IEA ATP binding
GO:0005768 IEA endosome
GO:0006468 IEA protein phosphorylation
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0035091 IEA phosphatidylinositol binding
GO:2001240 IDA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062460 C24H8orf44 C8orf44-SGK3 readthrough protein_coding Danio_rerio
ENSG00000104205 SGK3 serum/glucocorticoid regulated kinase family, member 3 protein_coding Homo_sapiens
ENSG00000270024 C8orf44-SGK3 C8orf44-SGK3 readthrough protein_coding Homo_sapiens

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