C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CASP8 and FADD-like apoptosis regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026031 Cflar 10090 + 1:58711508-58758884 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069333 Cflar-004 58713317-58755165 protein_coding
  ENSMUST00000097722 Cflar-002 58711551-58753976 protein_coding
  ENSMUST00000097723 Cflar-011 58711544-58717554 processed_transcript
  ENSMUST00000114309 Cflar-005 58713294-58733227 protein_coding
  ENSMUST00000114313 Cflar-003 58711560-58758884 protein_coding
  ENSMUST00000123032 Cflar-010 58730552-58752453 processed_transcript
  ENSMUST00000123553 Cflar-006 58713302-58723070 processed_transcript
  ENSMUST00000124567 Cflar-009 58711534-58713889 processed_transcript
  ENSMUST00000140940 Cflar-001 58711508-58754341 processed_transcript
  ENSMUST00000149874 Cflar-007 58711508-58713886 processed_transcript
  ENSMUST00000156870 Cflar-008 58711516-58714303 processed_transcript
  ENSMUST00000164900 Cflar-012 58711510-58731246 processed_transcript
  ENSMUST00000189858 Cflar-013 58713886-58717562 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069333ENSMUST00000114313ENSMUST00000123032ENSMUST00000140940ENSMUST00000149874
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069333 5.833±0.04 6.132±0.59 N/A N/A 6.269±0.00 4.143±0.52 N/A N/A N/A 8.343±0.79 N/A 5.438±1.21 N/A N/A
ENSMUST00000114313 N/A 11.647±0.00 4.944±0.00 0.577±0.00 N/A N/A 1.601±0.00 N/A 1.928±1.10 N/A 1.033±0.17 3.402±1.30 2.649±1.53 N/A
ENSMUST00000123032 N/A N/A N/A 9.020±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140940 N/A N/A N/A N/A N/A 3.750±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000149874 N/A 21.160±3.58 N/A N/A N/A 12.366±1.37 N/A 33.801±4.93 N/A N/A N/A 19.053±3.34 N/A 3.350±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089O CIL_00089O_0002 VISTA 1:58652904-59256413

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004197 IEA cysteine-type endopeptidase activity
GO:0006508 IEA proteolysis
GO:0006915 IEA apoptotic process
GO:0007519 IMP skeletal muscle tissue development
GO:0014732 IMP skeletal muscle atrophy
GO:0014842 IMP regulation of satellite cell proliferation
GO:0014866 IMP skeletal myofibril assembly
GO:0042981 IEA regulation of apoptotic process
GO:0043403 IMP skeletal muscle tissue regeneration
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:1901740 IMP negative regulation of myoblast fusion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055966 cflara CASP8 and FADD-like apoptosis regulator a protein_coding Danio_rerio
ENSDARG00000074802 cflarb CASP8 and FADD-like apoptosis regulator b protein_coding Danio_rerio
ENSG00000003402 CFLAR CASP8 and FADD-like apoptosis regulator protein_coding Homo_sapiens

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