C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: villin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026175 Vil1 10090 + 1:74409376-74435559 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027366 Vil1-001 74409376-74435559 protein_coding
  ENSMUST00000159749 Vil1-003 74419053-74423018 protein_coding
  ENSMUST00000161087 Vil1-002 74421416-74423011 retained_intron
  ENSMUST00000163018 Vil1-004 74423686-74425966 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyPlacentaENSMUST00000027366
Transcript ID Colon Kidney Placenta
ENSMUST00000027366 100.992±12.42 36.507±3.05 22.202±0.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000650 CIL_000650_0002 CGP 1:74391509-74435559
CIL_000651 CIL_000651_0002 CGP 1:74409376-74544284

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005902 ISS microvillus
GO:0005903 TAS brush border
GO:0007173 ISS epidermal growth factor receptor signaling pathway
GO:0008360 ISS regulation of cell shape
GO:0009617 IEA response to bacterium
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0030027 IDA lamellipodium
GO:0030041 ISS actin filament polymerization
GO:0030042 ISS actin filament depolymerization
GO:0030175 IDA filopodium
GO:0030335 ISS positive regulation of cell migration
GO:0030855 IEA epithelial cell differentiation
GO:0032233 ISS positive regulation of actin filament bundle assembly
GO:0032432 ISS actin filament bundle
GO:0032433 IDA filopodium tip
GO:0035727 ISS lysophosphatidic acid binding
GO:0035729 IDA cellular response to hepatocyte growth factor stimulus
GO:0042802 IEA identical protein binding
GO:0042803 ISS protein homodimerization activity
GO:0043027 IMP cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0051014 IEA actin filament severing
GO:0051015 ISS actin filament binding
GO:0051125 ISS regulation of actin nucleation
GO:0051693 ISS actin filament capping
GO:0060327 IEA cytoplasmic actin-based contraction involved in cell motility
GO:0061041 IDA regulation of wound healing
GO:0070062 IEA extracellular vesicular exosome
GO:0071364 ISS cellular response to epidermal growth factor stimulus
GO:2000392 IDA regulation of lamellipodium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040466 vil1 villin 1 protein_coding Danio_rerio
ENSG00000127831 VIL1 villin 1 protein_coding Homo_sapiens

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