C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1F (PP2C domain containing)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026181 Ppm1f 10090 + 16:16896469-16927364 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027373 Ppm1f-001 16896469-16927364 protein_coding
  ENSMUST00000145978 Ppm1f-002 16896574-16915194 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027373ENSMUST00000145978
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027373 16.376±1.93 14.888±1.00 9.483±0.46 11.866±2.48 8.938±2.38 3.763±0.14 6.769±0.21 7.201±0.37 5.946±1.02 26.368±1.85 3.947±0.48 12.037±2.12 7.896±2.61 11.958±4.33
ENSMUST00000145978 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.472±0.00 N/A 11.438±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PT CIL_0008PT_0002 VISTA 16:16870677-17470725

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004722 ISS protein serine/threonine phosphatase activity
GO:0005515 IEA protein binding
GO:0005829 ISS cytosol
GO:0006469 ISS negative regulation of protein kinase activity
GO:0010628 ISS positive regulation of gene expression
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0010811 ISS positive regulation of cell-substrate adhesion
GO:0016576 IEA histone dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0033137 ISS negative regulation of peptidyl-serine phosphorylation
GO:0033192 ISS calmodulin-dependent protein phosphatase activity
GO:0035690 ISS cellular response to drug
GO:0035970 ISS peptidyl-threonine dephosphorylation
GO:0043234 ISS protein complex
GO:0043280 ISS positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044387 ISS negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045927 ISS positive regulation of growth
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050921 ISS positive regulation of chemotaxis
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0051894 ISS positive regulation of focal adhesion assembly
GO:0097193 ISS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005786 ppm1f protein phosphatase 1F (PP2C domain containing) protein_coding Danio_rerio
ENSG00000100034 PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F protein_coding Homo_sapiens

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