C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1F
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100034 PPM1F 9606 - 22:21919420-21952837 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263212 PPM1F-001 21919420-21952837 protein_coding
  ENST00000397495 PPM1F-003 21924876-21952831 protein_coding
  ENST00000407142 PPM1F-002 21919427-21938584 protein_coding
  ENST00000424647 PPM1F-007 21934024-21938576 protein_coding
  ENST00000445205 PPM1F-004 21931266-21940657 protein_coding
  ENST00000484588 PPM1F-005 21924876-21931248 processed_transcript
  ENST00000486259 PPM1F-008 21936962-21938531 processed_transcript
  ENST00000496143 PPM1F-006 21923125-21926062 processed_transcript
  ENST00000497072 PPM1F-009 21952020-21952821 processed_transcript
  ENST00000623652 PPM1F-010 21932714-21936929 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263212ENST00000397495
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263212 10.222±0.00 9.448±0.00 0.850±0.00 1.431±0.01 3.049±1.26 5.033±0.00 2.232±1.80 1.716±1.01 1.366±0.68 5.675±4.21 0.687±0.00 4.000±2.48 10.508±3.60 3.217±1.89
ENST00000397495 N/A N/A 1.245±0.00 N/A N/A N/A 0.508±0.00 1.215±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003KZ CIL_0003KZ_0002 CGP 22:21754500-21952837
CIL_0003KY CIL_0003KY_0002 CGP 22:21919420-21982816

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004722 IEA:IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006470 IEA protein dephosphorylation
GO:0010628 IMP positive regulation of gene expression
GO:0010634 IMP positive regulation of epithelial cell migration
GO:0010811 IMP positive regulation of cell-substrate adhesion
GO:0016576 IEA histone dephosphorylation
GO:0016791 IDA phosphatase activity
GO:0033137 IDA negative regulation of peptidyl-serine phosphorylation
GO:0033192 IDA calmodulin-dependent protein phosphatase activity
GO:0035690 IDA cellular response to drug
GO:0035970 IDA peptidyl-threonine dephosphorylation
GO:0043234 IDA protein complex
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044387 IDA negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045927 IMP positive regulation of growth
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050921 IMP positive regulation of chemotaxis
GO:0051496 IDA positive regulation of stress fiber assembly
GO:0051894 IMP positive regulation of focal adhesion assembly
GO:0097193 IDA intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005786 ppm1f protein phosphatase 1F (PP2C domain containing) protein_coding Danio_rerio
ENSMUSG00000026181 Ppm1f protein phosphatase 1F (PP2C domain containing) protein_coding Mus_musculus

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