C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PAS domain containing serine/threonine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026274 Pask 10090 - 1:93308770-93343482 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027493 Pask-001 93308778-93342789 protein_coding
  ENSMUST00000128253 Pask-003 93337449-93343482 protein_coding
  ENSMUST00000128655 Pask-004 93308770-93317413 retained_intron
  ENSMUST00000133886 Pask-005 93309838-93313148 retained_intron
  ENSMUST00000139028 Pask-002 93317828-93343465 retained_intron
  ENSMUST00000148355 Pask-006 93310085-93311344 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLiverOvaryPlacentaTestisENSMUST00000027493ENSMUST00000139028
Transcript ID Adipose Adrenal Brain Breast Colon Liver Ovary Placenta Testis
ENSMUST00000027493 0.769±0.00 0.612±0.02 4.279±0.00 0.473±0.00 0.776±0.18 3.042±1.41 1.162±0.18 1.609±0.30 12.611±3.41
ENSMUST00000139028 N/A 0.740±0.05 1.456±0.00 0.585±0.00 N/A 1.481±0.00 1.954±0.38 N/A 3.050±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000474 CIL_000474_0002 CGP 1:93299211-93343482
CIL_000475 CIL_000475_0002 CGP 1:93308770-93373489

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005622 ISA intracellular
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0006468 ISS protein phosphorylation
GO:0007165 IEA signal transduction
GO:0035091 ISS phosphatidylinositol binding
GO:0043576 IMP regulation of respiratory gaseous exchange
GO:0045719 ISS negative regulation of glycogen biosynthetic process
GO:0046777 ISS protein autophosphorylation
GO:0070092 IMP regulation of glucagon secretion
GO:2000505 IMP regulation of energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075008 pask PAS domain containing serine/threonine kinase protein_coding Danio_rerio
ENSG00000115687 PASK PAS domain containing serine/threonine kinase protein_coding Homo_sapiens

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