C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peptidylglycine alpha-amidating monooxygenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026335 Pam 10090 - 1:97795114-98095646 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000058762 Pam-001 97821094-98095621 protein_coding
  ENSMUST00000097625 Pam-201 97821095-98095632 protein_coding
  ENSMUST00000159041 Pam-009 97795114-97840811 protein_coding
  ENSMUST00000159131 Pam-010 97837532-97840391 retained_intron
  ENSMUST00000159428 Pam-004 97933471-97977068 retained_intron
  ENSMUST00000159585 Pam-012 97821981-97834647 retained_intron
  ENSMUST00000159841 Pam-007 97854634-97894396 protein_coding
  ENSMUST00000160210 Pam-013 97822724-97825985 processed_transcript
  ENSMUST00000161071 Pam-006 97852925-97864464 retained_intron
  ENSMUST00000161567 Pam-002 97821100-97977255 protein_coding
  ENSMUST00000162426 Pam-005 97957396-97977244 processed_transcript
  ENSMUST00000162681 Pam-011 97821721-97840389 protein_coding
  ENSMUST00000162803 Pam-008 97825659-97840881 retained_intron
  ENSMUST00000163007 Pam-003 98057973-98095646 processed_transcript
  ENSMUST00000186731 Pam-014 98053990-98057883 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000058762ENSMUST00000097625ENSMUST00000159841ENSMUST00000161567ENSMUST00000162426ENSMUST00000162681ENSMUST00000162803ENSMUST00000186731
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000058762 5.385±0.73 24.957±0.00 28.042±4.75 14.449±6.72 3.059±0.00 18.028±2.54 N/A 5.018±0.00 1.541±0.52 16.728±5.78 2.367±0.63 7.642±1.46 2.280±0.61 1.173±0.18
ENSMUST00000097625 N/A 27.746±0.00 5.748±1.03 6.673±1.59 N/A 6.299±0.00 N/A 4.628±0.00 0.592±0.10 N/A 1.164±0.23 8.503±0.36 2.145±0.77 0.775±0.00
ENSMUST00000159841 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.158±0.00 4.725±0.00
ENSMUST00000161567 6.954±0.00 22.882±4.58 10.639±2.03 4.410±0.11 10.865±2.65 23.224±2.66 103.480±3.30 13.792±6.33 2.316±0.74 25.428±9.50 2.724±0.64 17.640±7.30 9.960±3.64 1.642±0.64
ENSMUST00000162426 N/A 125.234±51.69 N/A N/A N/A 42.466±12.58 N/A N/A N/A 132.299±0.00 N/A 27.395±2.40 N/A N/A
ENSMUST00000162681 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.298±0.00
ENSMUST00000162803 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.816±0.00 17.531±0.53 N/A
ENSMUST00000186731 0.129±0.06 0.076±0.05 0.178±0.01 N/A 0.154±0.09 0.159±0.06 0.063±0.00 0.745±0.20 0.035±0.01 0.335±0.08 N/A 0.240±0.11 0.161±0.02 0.028±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001519 IEA peptide amidation
GO:0004504 TAS peptidylglycine monooxygenase activity
GO:0004598 IEA peptidylamidoglycolate lyase activity
GO:0005507 IEA copper ion binding
GO:0005829 TAS cytosol
GO:0005887 TAS integral component of plasma membrane
GO:0006518 TAS peptide metabolic process
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0031418 IEA L-ascorbic acid binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042071 pam peptidylglycine alpha-amidating monooxygenase protein_coding Danio_rerio
ENSG00000145730 PAM peptidylglycine alpha-amidating monooxygenase protein_coding Homo_sapiens

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