C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: poly (ADP-ribose) polymerase family, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026496 Parp1 10090 + 1:180568955-180601253 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027777 Parp1-201 180568955-180601253 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027777
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027777 13.150±4.21 10.382±5.79 17.314±2.67 31.221±5.14 12.335±1.86 6.711±2.27 9.787±1.23 9.410±2.00 17.976±13.01 7.745±0.52 16.713±0.55 24.070±14.13 28.234±11.20 20.577±7.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CY CIL_0008CY_0002 VISTA 1:179968494-180569356

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IMP telomere maintenance
GO:0003677 IEA DNA binding
GO:0003950 ISO NAD+ ADP-ribosyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005635 IEA nuclear envelope
GO:0005654 IDA nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005730 IDA nucleolus
GO:0006259 IMP DNA metabolic process
GO:0006281 TAS DNA repair
GO:0006284 IMP base-excision repair
GO:0006302 IGI double-strand break repair
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0008134 IEA transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0016540 IEA protein autoprocessing
GO:0019899 IEA enzyme binding
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0032869 IEA cellular response to insulin stimulus
GO:0040009 IMP regulation of growth rate
GO:0042769 IEA DNA damage response, detection of DNA damage
GO:0042802 IEA identical protein binding
GO:0043234 IDA protein complex
GO:0044822 IEA poly(A) RNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0047485 IEA protein N-terminus binding
GO:0060391 IEA positive regulation of SMAD protein import into nucleus
GO:0070212 IEA protein poly-ADP-ribosylation
GO:0070412 IEA R-SMAD binding
GO:0071451 IDA cellular response to superoxide
GO:2000679 IEA positive regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019529 parp1 poly (ADP-ribose) polymerase family, member 1 protein_coding Danio_rerio
ENSG00000143799 PARP1 poly (ADP-ribose) polymerase 1 protein_coding Homo_sapiens

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