C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026596 Abl2 10090 + 1:156558786-156649568 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027888 Abl2-002 156559049-156642716 protein_coding
  ENSMUST00000166172 Abl2-001 156558987-156649568 protein_coding
  ENSMUST00000173929 Abl2-003 156558786-156625376 protein_coding
  ENSMUST00000190749 Abl2-004 156615923-156629993 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000166172ENSMUST00000173929
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000166172 1.714±0.33 1.668±0.44 2.345±0.04 4.613±1.47 1.852±1.14 0.649±0.24 0.692±0.04 1.777±0.33 0.705±0.30 3.075±0.79 0.801±0.32 3.405±1.44 2.953±1.64 1.505±0.88
ENSMUST00000173929 N/A 2.500±0.43 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.195±0.59 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001891 IDA phagocytic cup
GO:0004713 IDA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006909 IMP phagocytosis
GO:0006930 IGI substrate-dependent cell migration, cell extension
GO:0007015 IDA actin filament organization
GO:0007173 IGI epidermal growth factor receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007612 IMP learning
GO:0008542 IGI visual learning
GO:0010863 IEA positive regulation of phospholipase C activity
GO:0010976 IGI positive regulation of neuron projection development
GO:0015629 IDA actin cytoskeleton
GO:0016023 TAS cytoplasmic membrane-bounded vesicle
GO:0016322 IMP neuron remodeling
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021587 IGI cerebellum morphogenesis
GO:0022408 IGI negative regulation of cell-cell adhesion
GO:0030027 IDA lamellipodium
GO:0030145 IEA manganese ion binding
GO:0032092 IMP positive regulation of protein binding
GO:0034613 IMP cellular protein localization
GO:0035024 IGI negative regulation of Rho protein signal transduction
GO:0035640 IGI exploration behavior
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043197 IDA dendritic spine
GO:0046632 IGI alpha-beta T cell differentiation
GO:0048008 IGI platelet-derived growth factor receptor signaling pathway
GO:0048813 IGI dendrite morphogenesis
GO:0050885 IGI neuromuscular process controlling balance
GO:0051017 IDA actin filament bundle assembly
GO:0051353 IEA positive regulation of oxidoreductase activity
GO:0060020 IGI Bergmann glial cell differentiation
GO:0070374 IGI positive regulation of ERK1 and ERK2 cascade
GO:0071300 IEA cellular response to retinoic acid
GO:0097062 IGI dendritic spine maintenance
GO:1900042 IGI positive regulation of interleukin-2 secretion
GO:1902715 IGI positive regulation of interferon-gamma secretion
GO:1903053 IGI regulation of extracellular matrix organization
GO:2000096 IGI positive regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000352 IGI negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013841 abl2 v-abl Abelson murine leukemia viral oncogene homolog 2 protein_coding Danio_rerio
ENSG00000143322 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase protein_coding Homo_sapiens

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