C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sterol O-acyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026600 Soat1 10090 - 1:156424525-156474331 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051396 Soat1-003 156429793-156466804 protein_coding
  ENSMUST00000186420 Soat1-008 156430725-156432573 retained_intron
  ENSMUST00000187073 Soat1-006 156446411-156474197 retained_intron
  ENSMUST00000187507 Soat1-004 156440576-156474296 protein_coding
  ENSMUST00000187987 Soat1-007 156430983-156433019 retained_intron
  ENSMUST00000188027 Soat1-005 156446644-156474264 protein_coding
  ENSMUST00000189661 Soat1-001 156424525-156474331 protein_coding
  ENSMUST00000191379 Soat1-002 156440150-156474240 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051396ENSMUST00000187507ENSMUST00000188027ENSMUST00000189661
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051396 8.320±6.29 75.662±29.67 4.355±0.18 1.156±0.34 6.612±1.71 13.759±3.06 1.203±0.18 4.594±0.83 4.139±4.65 28.161±4.18 0.239±0.21 95.618±21.82 18.020±11.05 8.767±3.62
ENSMUST00000187507 N/A N/A N/A N/A 10.732±0.00 N/A 1.761±0.00 N/A N/A N/A N/A 53.249±2.76 N/A N/A
ENSMUST00000188027 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.411±0.00
ENSMUST00000189661 3.736±2.57 33.554±2.36 3.092±0.04 1.818±0.31 2.350±0.66 4.076±0.47 0.561±0.09 2.218±0.17 1.955±2.20 14.961±0.98 0.190±0.06 33.339±7.81 4.550±3.30 3.424±1.48

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0004772 IDA sterol O-acyltransferase activity
GO:0005515 IEA protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0008203 IDA cholesterol metabolic process
GO:0010742 IEA macrophage derived foam cell differentiation
GO:0010878 IEA cholesterol storage
GO:0015485 IEA cholesterol binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0033344 IEA cholesterol efflux
GO:0034379 IEA very-low-density lipoprotein particle assembly
GO:0034435 IEA cholesterol esterification
GO:0034736 IEA cholesterol O-acyltransferase activity
GO:0042986 IEA positive regulation of amyloid precursor protein biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062297 soat1 sterol O-acyltransferase 1 protein_coding Danio_rerio
ENSG00000057252 SOAT1 sterol O-acyltransferase 1 protein_coding Homo_sapiens

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