C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sterol O-acyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000189661 Soat1-001 ENSMUSG00000026600 10090 - 1:156424525-156474331 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000189661
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000189661 3.736±2.57 33.554±2.36 3.092±0.04 1.818±0.31 2.350±0.66 4.076±0.47 0.561±0.09 2.218±0.17 1.955±2.20 14.961±0.98 0.190±0.06 33.339±7.81 4.550±3.30 3.424±1.48

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0004772 IDA sterol O-acyltransferase activity
GO:0005515 IEA protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0008203 IDA cholesterol metabolic process
GO:0010742 IEA macrophage derived foam cell differentiation
GO:0010878 IEA cholesterol storage
GO:0015485 IEA cholesterol binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0033344 IEA cholesterol efflux
GO:0034379 IEA very-low-density lipoprotein particle assembly
GO:0034435 IEA cholesterol esterification
GO:0034736 IEA cholesterol O-acyltransferase activity
GO:0042986 IEA positive regulation of amyloid precursor protein biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000367619 SOAT1-001 protein_coding Homo_sapiens 0 1580
ENST00000454997 AFG3L1P-012 retained_intron Homo_sapiens 0.0000000002 73
ENST00000539888 SOAT1-201 protein_coding Homo_sapiens 0 1531
ENST00000540564 SOAT1-202 protein_coding Homo_sapiens 0 1495

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