C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isoleucine-tRNA synthetase 2, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026618 Iars2 10090 - 1:185284726-185329396 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027921 Iars2-001 185284726-185329396 protein_coding
  ENSMUST00000110974 Iars2-004 185311846-185329396 protein_coding
  ENSMUST00000110975 Iars2-005 185295038-185329396 protein_coding
  ENSMUST00000131770 Iars2-002 185285569-185288282 processed_transcript
  ENSMUST00000153211 Iars2-003 185321183-185329396 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027921ENSMUST00000110974ENSMUST00000110975
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027921 16.802±3.88 15.173±1.56 12.771±3.15 11.130±0.83 14.637±1.84 13.421±4.33 11.652±5.21 17.815±3.04 9.114±2.06 12.888±0.45 8.669±1.31 15.244±2.55 11.966±3.42 4.264±1.19
ENSMUST00000110974 N/A N/A N/A N/A 12.541±0.00 N/A N/A N/A N/A N/A N/A 7.220±0.00 N/A N/A
ENSMUST00000110975 N/A 13.597±0.00 N/A N/A 7.193±0.00 10.803±1.95 N/A N/A N/A 7.762±0.00 3.654±0.17 11.035±3.62 13.293±0.88 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002161 IEA aminoacyl-tRNA editing activity
GO:0004822 IEA isoleucine-tRNA ligase activity
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0006428 IEA isoleucyl-tRNA aminoacylation
GO:0006450 IEA regulation of translational fidelity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044134 iars2 isoleucine-tRNA synthetase 2, mitochondrial protein_coding Danio_rerio
ENSG00000067704 IARS2 isoleucyl-tRNA synthetase 2, mitochondrial protein_coding Homo_sapiens

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