Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	isoleucyl-tRNA synthetase 2, mitochondrial
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000067704	IARS2	9606	+	1:220094102-220148041	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000366922		IARS2-001	220094102-220148041	protein_coding
	ENST00000467924		IARS2-004	220140181-220143344	processed_transcript
	ENST00000488777		IARS2-002	220137642-220140218	processed_transcript
	ENST00000490891		IARS2-003	220114451-220134846	processed_transcript

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000366922	28.347±0.00	20.086±0.00	8.401±0.00	11.440±3.93	19.052±9.99	15.159±3.60	14.910±8.76	20.024±5.49	10.093±4.63	7.961±2.27	10.724±6.10	18.650±6.89	20.079±8.08	26.127±0.30

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_000123	CIL_000123_0002	CGP	1:220094102-220272454

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000166	IEA	nucleotide binding
GO:0002161	IEA	aminoacyl-tRNA editing activity
GO:0003824	IEA	catalytic activity
GO:0004812	IEA	aminoacyl-tRNA ligase activity
GO:0004822	IEA	isoleucine-tRNA ligase activity
GO:0005524	IEA	ATP binding
GO:0005737	IDA:IEA	cytoplasm
GO:0005739	IDA	mitochondrion
GO:0005759	TAS	mitochondrial matrix
GO:0006418	TAS:IEA	tRNA aminoacylation for protein translation
GO:0006428	IEA	isoleucyl-tRNA aminoacylation
GO:0006450	IEA	regulation of translational fidelity
GO:0010467	TAS	gene expression

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000044134	iars2	isoleucine-tRNA synthetase 2, mitochondrial	protein_coding	Danio_rerio
ENSMUSG00000026618	Iars2	isoleucine-tRNA synthetase 2, mitochondrial	protein_coding	Mus_musculus

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