C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cubilin (intrinsic factor-cobalamin receptor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026726 Cubn 10090 - 2:13276338-13491924 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000091436 Cubn-001 13276338-13491924 protein_coding
  ENSMUST00000148506 Cubn-002 13456640-13459480 retained_intron
  ENSMUST00000152078 Cubn-003 13445021-13455624 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000091436ENSMUST00000152078
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000091436 0.026±0.01 0.014±0.01 0.022±0.00 0.026±0.00 0.047±0.02 0.123±0.13 0.015±0.00 21.467±6.59 0.015±0.01 0.009±0.00 0.036±0.02 23.649±29.68 0.071±0.04
ENSMUST00000152078 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.085±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00063X CIL_00063X_0003 CGP 2:13076967-13491924
CIL_0000IU CIL_0000IU_0003 CGP 2:13276338-13544664

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005764 IEA lysosome
GO:0005768 IDA endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005903 IDA brush border
GO:0005905 IDA coated pit
GO:0006898 IMP receptor-mediated endocytosis
GO:0008203 IEA cholesterol metabolic process
GO:0016324 IDA apical plasma membrane
GO:0030139 IDA endocytic vesicle
GO:0031419 IEA cobalamin binding
GO:0042803 IEA protein homodimerization activity
GO:0042953 IDA lipoprotein transport
GO:0045177 IDA apical part of cell
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087013 cubn cubilin (intrinsic factor-cobalamin receptor) protein_coding Danio_rerio
ENSG00000107611 CUBN cubilin (intrinsic factor-cobalamin receptor) protein_coding Homo_sapiens

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