C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 2 receptor, alpha chain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026770 Il2ra 10090 + 2:11642792-11693191 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028111 Il2ra-001 11642792-11693191 protein_coding
  ENSMUST00000150890 Il2ra-002 11642850-11648637 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028111ENSMUST00000150890
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028111 0.393±0.03 0.058±0.04 0.161±0.08 0.020±0.01 1.785±0.38 0.181±0.08 0.037±0.00 0.155±0.05 0.034±0.02 0.235±0.04 0.163±0.07 0.140±0.08 0.045±0.02 0.057±0.02
ENSMUST00000150890 N/A 0.317±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.354±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0004911 IMP interleukin-2 receptor activity
GO:0005515 IPI protein binding
GO:0006924 IMP activation-induced cell death of T cells
GO:0007219 IGI Notch signaling pathway
GO:0008144 IEA drug binding
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0019976 IPI interleukin-2 binding
GO:0038110 IMP interleukin-2-mediated signaling pathway
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042104 IMP positive regulation of activated T cell proliferation
GO:0042130 IMP negative regulation of T cell proliferation
GO:0043029 IMP T cell homeostasis
GO:0045582 IEA positive regulation of T cell differentiation
GO:0046013 IMP regulation of T cell homeostatic proliferation
GO:0050672 IMP negative regulation of lymphocyte proliferation
GO:0050687 IEA negative regulation of defense response to virus
GO:0050728 IMP negative regulation of inflammatory response
GO:0050777 IEA negative regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000134460 IL2RA interleukin 2 receptor, alpha protein_coding Homo_sapiens

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