C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 2 receptor, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134460 IL2RA 9606 - 10:6010689-6062325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256876 IL2RA-004 6012797-6062290 protein_coding
  ENST00000379954 IL2RA-002 6012071-6062309 protein_coding
  ENST00000379959 IL2RA-001 6010689-6062325 protein_coding
  ENST00000447847 IL2RA-005 6019453-6026001 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256876ENST00000379954ENST00000379959ENST00000447847
Transcript ID Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256876 N/A 0.036±0.00 0.693±0.00 N/A N/A N/A N/A 0.916±0.00 N/A 0.293±0.21 1.130±0.30 N/A
ENST00000379954 N/A 0.165±0.00 0.301±0.00 N/A N/A 0.144±0.04 N/A 0.504±0.05 N/A 0.213±0.03 0.423±0.00 0.033±0.00
ENST00000379959 4.209±0.00 N/A 0.258±0.02 0.318±0.00 0.120±0.00 N/A 0.103±0.00 N/A 0.019±0.00 0.350±0.19 0.968±0.44 0.065±0.00
ENST00000447847 N/A N/A N/A 1.003±0.57 N/A N/A 0.791±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0004911 IEA interleukin-2 receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006915 TAS apoptotic process
GO:0006924 IEA activation-induced cell death of T cells
GO:0006955 TAS immune response
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007219 IEA Notch signaling pathway
GO:0008144 IEA drug binding
GO:0008283 TAS cell proliferation
GO:0009897 IEA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0019976 IEA interleukin-2 binding
GO:0038110 TAS interleukin-2-mediated signaling pathway
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042104 IEA positive regulation of activated T cell proliferation
GO:0042130 IEA negative regulation of T cell proliferation
GO:0043029 IEA T cell homeostasis
GO:0045582 IEA positive regulation of T cell differentiation
GO:0046013 IEA regulation of T cell homeostatic proliferation
GO:0050672 IEA negative regulation of lymphocyte proliferation
GO:0050687 IEA negative regulation of defense response to virus
GO:0050728 IEA negative regulation of inflammatory response
GO:0050777 IEA negative regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026770 Il2ra interleukin 2 receptor, alpha chain protein_coding Mus_musculus

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