C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activin A receptor, type IC
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026834 Acvr1c 10090 - 2:58267453-58357895 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028178 Acvr1c-001 58267453-58357895 protein_coding
  ENSMUST00000100085 Acvr1c-002 58271822-58324807 protein_coding
  ENSMUST00000112607 Acvr1c-004 58274735-58357752 protein_coding
  ENSMUST00000112608 Acvr1c-003 58274735-58357752 protein_coding
  ENSMUST00000154453 Acvr1c-005 58296135-58324807 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028178ENSMUST00000100085ENSMUST00000112607ENSMUST00000112608ENSMUST00000154453
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028178 7.956±3.55 4.389±1.56 0.116±0.04 0.946±0.00 4.476±1.11 0.828±0.22 0.174±0.12 0.329±0.05 0.009±0.00 0.274±0.12 0.057±0.03 0.781±0.29 0.043±0.07 0.072±0.03
ENSMUST00000100085 N/A N/A N/A 0.021±0.00 N/A N/A 0.085±0.00 N/A 0.003±0.00 0.028±0.00 N/A N/A N/A 0.108±0.05
ENSMUST00000112607 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.290±0.09 N/A N/A
ENSMUST00000112608 2.335±0.00 N/A N/A N/A N/A 0.357±0.00 N/A N/A 0.020±0.00 N/A N/A N/A 0.021±0.01 0.294±0.18
ENSMUST00000154453 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.123±0.00 N/A 0.734±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000755 CIL_000755_0002 CGP 2:58129137-58357895
CIL_000752 CIL_000752_0002 CGP 2:58267453-58567157

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002021 IMP response to dietary excess
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0009749 IMP response to glucose
GO:0016021 IEA integral component of membrane
GO:0016361 ISS activin receptor activity, type I
GO:0019838 ISS growth factor binding
GO:0019915 IMP lipid storage
GO:0023014 IEA signal transduction by phosphorylation
GO:0030154 ISS cell differentiation
GO:0030262 IEA apoptotic nuclear changes
GO:0032868 IMP response to insulin
GO:0038092 IEA nodal signaling pathway
GO:0038100 IEA nodal binding
GO:0042981 ISS regulation of apoptotic process
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046676 IMP negative regulation of insulin secretion
GO:0046872 IEA metal ion binding
GO:0048179 ISS activin receptor complex
GO:1901164 IEA negative regulation of trophoblast cell migration
GO:1901383 IEA negative regulation of chorionic trophoblast cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086172 CABZ01079442.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000123612 ACVR1C activin A receptor, type IC protein_coding Homo_sapiens

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