C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activin A receptor, type IC
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123612 ACVR1C 9606 - 2:157526767-157629005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000243349 ACVR1C-001 157526767-157629005 protein_coding
  ENST00000335450 ACVR1C-003 157533742-157628727 protein_coding
  ENST00000348328 ACVR1C-002 157533742-157628727 protein_coding
  ENST00000409680 ACVR1C-004 157533742-157597560 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000243349ENST00000335450ENST00000409680
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000243349 6.307±0.00 0.008±0.00 0.936±0.65 2.983±2.81 1.389±1.22 0.040±0.00 N/A 1.270±0.00 0.010±0.00 N/A 0.034±0.00 0.045±0.04 0.081±0.00
ENST00000335450 N/A 0.169±0.00 N/A 0.680±0.00 N/A N/A 0.134±0.00 0.225±0.00 0.042±0.00 0.235±0.03 N/A N/A N/A
ENST00000409680 N/A 0.146±0.00 N/A N/A N/A N/A N/A 0.996±0.00 N/A N/A 0.905±0.00 0.149±0.00 0.093±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000755 CIL_000755_0001 CGP 2:157414619-157629005
CIL_000752 CIL_000752_0001 CGP 2:157526767-157875862

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002021 IEA response to dietary excess
GO:0004672 IEA protein kinase activity
GO:0004675 IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006468 IC:IEA protein phosphorylation
GO:0009749 IEA response to glucose
GO:0016020 IEA membrane
GO:0016361 IDA activin receptor activity, type I
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019838 IPI growth factor binding
GO:0019915 IEA lipid storage
GO:0023014 IEA signal transduction by phosphorylation
GO:0030154 IDA cell differentiation
GO:0030262 IDA apoptotic nuclear changes
GO:0032868 IEA response to insulin
GO:0038092 IMP nodal signaling pathway
GO:0038100 IMP nodal binding
GO:0043280 IMP positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046676 IEA negative regulation of insulin secretion
GO:0046872 IC metal ion binding
GO:0048179 IDA activin receptor complex
GO:1901164 IDA negative regulation of trophoblast cell migration
GO:1901383 IMP negative regulation of chorionic trophoblast cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086172 CABZ01079442.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000026834 Acvr1c activin A receptor, type IC protein_coding Mus_musculus

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