C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin and metallopeptidase domain 33
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027318 Adam33 10090 - 2:131050591-131063814 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052104 Adam33-002 131051109-131063814 protein_coding
  ENSMUST00000110232 Adam33-001 131050817-131063814 protein_coding
  ENSMUST00000124481 Adam33-009 131062049-131063543 retained_intron
  ENSMUST00000127343 Adam33-013 131053221-131054059 processed_transcript
  ENSMUST00000128828 Adam33-008 131050591-131054036 retained_intron
  ENSMUST00000132071 Adam33-010 131053522-131054529 retained_intron
  ENSMUST00000132436 Adam33-003 131050825-131063569 retained_intron
  ENSMUST00000134742 Adam33-006 131051110-131056481 retained_intron
  ENSMUST00000135149 Adam33-007 131050863-131056367 protein_coding
  ENSMUST00000147333 Adam33-005 131057530-131063513 protein_coding
  ENSMUST00000149625 Adam33-012 131053090-131054516 processed_transcript
  ENSMUST00000183552 Adam33-004 131050875-131063545 nonsense_mediated_decay
  ENSMUST00000184921 Adam33-011 131053042-131054526 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052104ENSMUST00000110232ENSMUST00000128828ENSMUST00000132436ENSMUST00000134742ENSMUST00000135149ENSMUST00000147333ENSMUST00000183552
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052104 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.649±0.00 N/A 0.415±0.00 N/A
ENSMUST00000110232 1.679±0.00 N/A N/A N/A N/A N/A N/A N/A 0.140±0.03 1.886±0.00 0.444±0.09 N/A N/A 0.297±0.00
ENSMUST00000128828 N/A N/A N/A N/A 5.098±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000132436 3.307±0.92 1.130±0.29 41.241±6.08 0.232±0.01 5.561±1.29 4.584±0.74 0.707±0.19 0.390±0.04 0.180±0.10 3.741±0.62 0.710±0.15 4.214±1.93 0.514±0.47 0.467±0.21
ENSMUST00000134742 2.737±0.56 1.748±0.26 48.720±0.00 0.441±0.00 6.072±0.74 6.737±1.57 0.775±0.00 0.414±0.13 0.225±0.06 3.591±0.99 0.663±0.11 6.922±2.05 0.605±0.54 0.358±0.00
ENSMUST00000135149 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.593±0.00 4.346±0.00 0.368±0.26 N/A
ENSMUST00000147333 N/A N/A N/A 1.704±0.00 8.193±0.00 N/A N/A N/A N/A N/A 0.717±0.01 4.152±0.67 0.367±0.27 N/A
ENSMUST00000183552 2.908±0.70 1.207±0.58 26.438±4.74 0.335±0.00 5.783±0.63 6.583±1.21 1.231±0.49 0.362±0.10 0.093±0.03 2.943±0.52 0.586±0.00 3.792±0.83 0.512±0.02 0.290±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DE CIL_0003DE_0002 CGP 2:131039632-131063814
CIL_0003D8 CIL_0003D8_0002 CGP 2:131050591-131086765

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 NAS metalloendopeptidase activity
GO:0006508 NAS proteolysis
GO:0008270 NAS zinc ion binding
GO:0016021 NAS integral component of membrane
GO:0042035 NAS regulation of cytokine biosynthetic process
GO:0042127 NAS regulation of cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059693 adam19a a disintegrin and metalloproteinase domain 19a protein_coding Danio_rerio
ENSG00000149451 ADAM33 ADAM metallopeptidase domain 33 protein_coding Homo_sapiens

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