C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sprouty protein with EVH-1 domain 1, related sequence
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027351 Spred1 10090 + 2:117121374-117182279 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028829 Spred1-001 117121374-117182279 protein_coding
  ENSMUST00000110901 Spred1-002 117121638-117172854 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028829ENSMUST00000110901
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028829 4.760±1.83 22.299±8.93 6.337±0.28 7.838±1.72 4.780±1.75 5.593±2.93 2.568±0.30 3.707±0.67 2.373±0.44 8.757±1.22 1.055±0.13 13.418±7.74 1.804±0.92 0.606±0.17
ENSMUST00000110901 N/A N/A N/A 8.268±0.00 N/A N/A N/A N/A N/A N/A N/A 5.358±0.00 N/A 0.318±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006QQ CIL_0006QQ_0002 CGP 2:116878691-117182279
CIL_0006QP CIL_0006QP_0002 CGP 2:117121374-117271540

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IMP inactivation of MAPK activity
GO:0005173 IPI stem cell factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0010801 IDA negative regulation of peptidyl-threonine phosphorylation
GO:0010923 ISS negative regulation of phosphatase activity
GO:0019901 IPI protein kinase binding
GO:0019902 ISS phosphatase binding
GO:0030291 IDA protein serine/threonine kinase inhibitor activity
GO:0043517 IDA positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 IDA regulation of protein deacetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041449 spred1 sprouty-related, EVH1 domain containing 1 protein_coding Danio_rerio
ENSG00000166068 SPRED1 sprouty-related, EVH1 domain containing 1 protein_coding Homo_sapiens

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