C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-like 11 (apoptosis facilitator)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027381 Bcl2l11 10090 + 2:128126038-128162547 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019281 Bcl2l11-201 128126038-128160961 protein_coding
  ENSMUST00000089634 Bcl2l11-003 128126038-128131495 protein_coding
  ENSMUST00000103210 Bcl2l11-005 128126050-128161228 protein_coding
  ENSMUST00000103211 Bcl2l11-006 128126040-128158442 protein_coding
  ENSMUST00000110341 Bcl2l11-001 128126039-128162547 protein_coding
  ENSMUST00000129206 Bcl2l11-004 128127575-128130145 processed_transcript
  ENSMUST00000132201 Bcl2l11-007 128128131-128128737 processed_transcript
  ENSMUST00000146023 Bcl2l11-002 128126038-128130015 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019281ENSMUST00000103210ENSMUST00000103211ENSMUST00000110341ENSMUST00000132201
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019281 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.213±0.00 N/A
ENSMUST00000103210 N/A 3.276±0.35 N/A N/A N/A 0.856±0.12 N/A N/A N/A N/A N/A 1.507±0.12 0.328±0.15 0.890±0.46
ENSMUST00000103211 N/A N/A N/A 1.513±0.00 N/A N/A N/A N/A N/A N/A N/A 7.349±0.00 4.336±2.30 6.185±0.00
ENSMUST00000110341 5.097±3.67 11.383±1.20 4.122±0.25 1.963±0.47 7.578±2.51 4.348±0.93 2.857±0.68 2.664±0.41 1.583±0.82 10.439±1.36 1.200±0.42 5.772±2.94 1.142±0.31 1.801±0.19
ENSMUST00000132201 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.729±7.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047S CIL_00047S_0002 CGP 2:127838876-128162547

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IGI in utero embryonic development
GO:0001776 IGI leukocyte homeostasis
GO:0001782 IGI B cell homeostasis
GO:0001783 IGI B cell apoptotic process
GO:0001822 IGI kidney development
GO:0002260 IGI lymphocyte homeostasis
GO:0002262 IGI myeloid cell homeostasis
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0005874 IEA microtubule
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007160 IMP cell-matrix adhesion
GO:0007283 IGI spermatogenesis
GO:0007420 IEA brain development
GO:0008017 IDA microtubule binding
GO:0008584 IGI male gonad development
GO:0008630 ISO intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791 IGI post-embryonic development
GO:0010942 IEA positive regulation of cell death
GO:0019898 IDA extrinsic component of membrane
GO:0030879 IMP mammary gland development
GO:0032464 IEA positive regulation of protein homooligomerization
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0035148 IMP tube formation
GO:0042475 IGI odontogenesis of dentin-containing tooth
GO:0042981 IGI regulation of apoptotic process
GO:0043029 IMP T cell homeostasis
GO:0043065 IMP positive regulation of apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043280 IMP positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 IDA positive regulation of neuron apoptotic process
GO:0043583 IGI ear development
GO:0045787 IMP positive regulation of cell cycle
GO:0046620 IMP regulation of organ growth
GO:0048066 IGI developmental pigmentation
GO:0048070 IGI regulation of developmental pigmentation
GO:0048536 IGI spleen development
GO:0048538 IGI thymus development
GO:0048563 IMP post-embryonic organ morphogenesis
GO:0060139 IDA positive regulation of apoptotic process by virus
GO:0060154 IDA cellular process regulating host cell cycle in response to virus
GO:0070242 IGI thymocyte apoptotic process
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0097140 IEA BIM-BCL-xl complex
GO:0097141 IEA BIM-BCL-2 complex
GO:0097192 IGI extrinsic apoptotic signaling pathway in absence of ligand
GO:1902110 IGI positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902263 IGI apoptotic process involved in embryonic digit morphogenesis
GO:2000271 IEA positive regulation of fibroblast apoptotic process
GO:2001244 IEA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000153094 BCL2L11 BCL2-like 11 (apoptosis facilitator) protein_coding Homo_sapiens

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