C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-like 11 (apoptosis facilitator)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153094 BCL2L11 9606 + 2:111119378-111168447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308659 BCL2L11-011 111120914-111165048 protein_coding
  ENST00000337565 BCL2L11-201 111120914-111128844 protein_coding
  ENST00000357757 BCL2L11-202 111120914-111146281 protein_coding
  ENST00000361493 BCL2L11-014 111123746-111164231 nonsense_mediated_decay
  ENST00000393252 BCL2L11-013 111122670-111123960 protein_coding
  ENST00000393256 BCL2L11-001 111120929-111168447 protein_coding
  ENST00000405953 BCL2L11-010 111123746-111128837 protein_coding
  ENST00000415458 BCL2L11-006 111123746-111164231 nonsense_mediated_decay
  ENST00000431217 BCL2L11-003 111123746-111164352 nonsense_mediated_decay
  ENST00000432179 BCL2L11-012 111119378-111124112 protein_coding
  ENST00000433098 BCL2L11-002 111122694-111164643 nonsense_mediated_decay
  ENST00000436733 BCL2L11-007 111123746-111164231 nonsense_mediated_decay
  ENST00000437029 BCL2L11-008 111123746-111164231 nonsense_mediated_decay
  ENST00000438054 BCL2L11-004 111123752-111146284 protein_coding
  ENST00000439718 BCL2L11-005 111123746-111164643 nonsense_mediated_decay
  ENST00000452231 BCL2L11-009 111123746-111164231 nonsense_mediated_decay
  ENST00000610735 BCL2L11-203 111120914-111168445 protein_coding
  ENST00000615946 BCL2L11-204 111120914-111168445 protein_coding
  ENST00000619294 BCL2L11-205 111120914-111168445 protein_coding
  ENST00000620862 BCL2L11-206 111120914-111168445 protein_coding
  ENST00000621302 BCL2L11-207 111120914-111168445 protein_coding
  ENST00000622509 BCL2L11-208 111120914-111168445 protein_coding
  ENST00000622612 BCL2L11-209 111120914-111168445 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308659ENST00000337565ENST00000393256ENST00000433098ENST00000439718ENST00000615946ENST00000619294ENST00000620862ENST00000621302ENST00000622509
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308659 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.242±0.00 N/A N/A N/A
ENST00000337565 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.350±0.00 N/A N/A
ENST00000393256 1.230±0.00 N/A 0.436±0.00 0.439±0.00 0.781±0.00 0.540±0.00 N/A 0.333±0.02 0.865±0.17 N/A 1.121±0.16 0.402±0.00 N/A
ENST00000433098 N/A N/A N/A N/A N/A N/A N/A 0.544±0.00 N/A N/A N/A N/A 6.217±0.00
ENST00000439718 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.698±0.00 N/A N/A N/A
ENST00000615946 N/A 0.410±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000619294 N/A 0.404±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000620862 N/A N/A N/A N/A N/A N/A 1.367±0.00 N/A N/A N/A 3.278±0.00 0.879±0.00 2.233±0.65
ENST00000621302 0.978±0.00 0.372±0.00 N/A 0.136±0.00 N/A N/A N/A 0.272±0.00 N/A N/A 0.596±0.00 N/A N/A
ENST00000622509 N/A N/A N/A N/A N/A N/A N/A N/A 0.663±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047S CIL_00047S_0001 CGP 2:110732573-111168447

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001776 IEA leukocyte homeostasis
GO:0001782 IEA B cell homeostasis
GO:0001783 IEA B cell apoptotic process
GO:0001822 IEA kidney development
GO:0002260 IEA lymphocyte homeostasis
GO:0002262 IEA myeloid cell homeostasis
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0005874 IDA microtubule
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007160 IEA cell-matrix adhesion
GO:0007283 IEA spermatogenesis
GO:0007420 IEA brain development
GO:0008017 IDA microtubule binding
GO:0008584 IEA male gonad development
GO:0008630 IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791 IEA post-embryonic development
GO:0010942 IEA positive regulation of cell death
GO:0019898 IEA extrinsic component of membrane
GO:0030879 IEA mammary gland development
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0035148 IEA tube formation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042981 IEA regulation of apoptotic process
GO:0043029 IEA T cell homeostasis
GO:0043065 IMP positive regulation of apoptotic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043583 IEA ear development
GO:0045787 IEA positive regulation of cell cycle
GO:0046620 IEA regulation of organ growth
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048066 IEA developmental pigmentation
GO:0048070 IEA regulation of developmental pigmentation
GO:0048536 IEA spleen development
GO:0048538 IEA thymus development
GO:0048563 IEA post-embryonic organ morphogenesis
GO:0060139 IEA positive regulation of apoptotic process by virus
GO:0060154 IEA cellular process regulating host cell cycle in response to virus
GO:0070242 IEA thymocyte apoptotic process
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097140 IDA BIM-BCL-xl complex
GO:0097141 IDA BIM-BCL-2 complex
GO:0097190 TAS apoptotic signaling pathway
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1902110 IEA positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902263 IEA apoptotic process involved in embryonic digit morphogenesis
GO:2000271 IDA positive regulation of fibroblast apoptotic process
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027381 Bcl2l11 BCL2-like 11 (apoptosis facilitator) protein_coding Mus_musculus

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