C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiopoietin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027460 Angpt4 10090 + 2:151911210-151945337 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028955 Angpt4-001 151911210-151945337 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028955
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028955 1.162±0.43 0.592±0.27 1.046±0.24 0.033±0.01 0.264±0.10 0.767±0.36 0.352±0.08 0.459±0.17 0.065±0.04 1.290±0.32 0.077±0.03 8.606±3.81 3.026±1.41 0.888±0.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005FN CIL_0005FN_0002 CGP 2:151842927-151945337

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005172 TAS vascular endothelial growth factor receptor binding
GO:0005615 IEA extracellular space
GO:0007171 IEA activation of transmembrane receptor protein tyrosine kinase activity
GO:0007492 TAS endoderm development
GO:0010595 IEA positive regulation of endothelial cell migration
GO:0016525 IEA negative regulation of angiogenesis
GO:0030297 IEA transmembrane receptor protein tyrosine kinase activator activity
GO:0030971 IEA receptor tyrosine kinase binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0043537 IEA negative regulation of blood vessel endothelial cell migration
GO:0045766 IEA positive regulation of angiogenesis
GO:0048014 TAS Tie signaling pathway
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076787 angpt4 angiopoietin 4 protein_coding Danio_rerio
ENSG00000101280 ANGPT4 angiopoietin 4 protein_coding Homo_sapiens

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