C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light polypeptide kinase 2, skeletal muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027470 Mylk2 10090 + 2:152911352-152923068 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028970 Mylk2-001 152911352-152923068 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028970
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028970 0.081±0.03 0.200±0.00 0.006±0.00 15.911±15.90 0.026±0.02 0.101±0.05 0.268±0.24 0.018±0.02 0.428±0.44 317.032±39.38 0.069±0.04 0.024±0.01 0.019±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K5 CIL_0008K5_0002 VISTA 2:152434876-153035572
CIL_00089Z CIL_00089Z_0002 VISTA 2:152488201-153091382
CIL_0008N4 CIL_0008N4_0002 VISTA 2:152517372-153118197
CIL_000319 CIL_000319_0003 CGP 2:152847964-152923068
CIL_0000JB CIL_0000JB_0002 CGP 2:152911352-152933208

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004687 IEA myosin light chain kinase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006941 IEA striated muscle contraction
GO:0007274 IGI neuromuscular synaptic transmission
GO:0010628 IEA positive regulation of gene expression
GO:0014816 IMP skeletal muscle satellite cell differentiation
GO:0018107 IEA peptidyl-threonine phosphorylation
GO:0032971 IEA regulation of muscle filament sliding
GO:0035914 NAS skeletal muscle cell differentiation
GO:0046777 IEA protein autophosphorylation
GO:0055007 NAS cardiac muscle cell differentiation
GO:0055008 IEA cardiac muscle tissue morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031698 mylk2 myosin light chain kinase 2 protein_coding Danio_rerio
ENSG00000101306 MYLK2 myosin light chain kinase 2 protein_coding Homo_sapiens

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