C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027720 Il2 10090 - 3:37120523-37125959 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029275 Il2-001 37120523-37125959 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastKidneyLiverOvaryPlacentaTestisENSMUST00000029275
Transcript ID Bladder Brain Breast Kidney Liver Ovary Placenta Testis
ENSMUST00000029275 0.028±0.00 0.093±0.08 0.491±0.28 0.092±0.04 0.042±0.05 0.060±0.00 0.030±0.02 0.067±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AD CIL_0007AD_0002 CGP 3:36863106-37121924
CIL_0007AE CIL_0007AE_0002 CGP 3:37063527-37125959
CIL_0007AF CIL_0007AF_0002 CGP 3:37120523-37232618

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002903 ISO negative regulation of B cell apoptotic process
GO:0005125 IDA cytokine activity
GO:0005134 IDA interleukin-2 receptor binding
GO:0005615 IDA extracellular space
GO:0006955 IEA immune response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0030246 IEA carbohydrate binding
GO:0030890 ISO positive regulation of B cell proliferation
GO:0031851 IEA kappa-type opioid receptor binding
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0032740 IEA positive regulation of interleukin-17 production
GO:0042102 IDA positive regulation of T cell proliferation
GO:0042104 IDA positive regulation of activated T cell proliferation
GO:0042523 IDA positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0043208 IEA glycosphingolipid binding
GO:0045582 IEA positive regulation of T cell differentiation
GO:0045591 IEA positive regulation of regulatory T cell differentiation
GO:0045822 IEA negative regulation of heart contraction
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046013 IMP regulation of T cell homeostatic proliferation
GO:0048304 IMP positive regulation of isotype switching to IgG isotypes
GO:0050672 IMP negative regulation of lymphocyte proliferation
GO:0050728 IMP negative regulation of inflammatory response
GO:0051024 IMP positive regulation of immunoglobulin secretion
GO:0060999 IEA positive regulation of dendritic spine development
GO:0097192 IDA extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000109471 IL2 interleukin 2 protein_coding Homo_sapiens

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