C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027931 Npr1 10090 - 3:90450591-90465866 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029540 Npr1-001 90450591-90465866 protein_coding
  ENSMUST00000124760 Npr1-002 90457418-90461421 nonsense_mediated_decay
  ENSMUST00000142243 Npr1-004 90455103-90457476 processed_transcript
  ENSMUST00000146991 Npr1-003 90457399-90458939 retained_intron
  ENSMUST00000152510 Npr1-005 90450710-90451781 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029540ENSMUST00000124760ENSMUST00000142243
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029540 23.171±7.71 46.363±17.05 8.131±0.99 0.912±0.22 18.184±3.43 1.194±0.37 4.776±1.65 11.476±2.19 2.600±1.29 29.360±9.85 3.126±0.54 31.448±10.87 7.843±4.03 10.542±3.70
ENSMUST00000124760 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 31.851±0.00 3.947±0.00 N/A
ENSMUST00000142243 N/A N/A N/A N/A 42.428±0.00 N/A N/A N/A N/A N/A N/A 38.775±0.00 5.415±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004383 IDA guanylate cyclase activity
GO:0004672 IEA protein kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005886 IEA plasma membrane
GO:0006182 IEA cGMP biosynthetic process
GO:0006468 IEA protein phosphorylation
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007168 IEA receptor guanylyl cyclase signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016941 ISS natriuretic peptide receptor activity
GO:0017046 IEA peptide hormone binding
GO:0019901 IEA protein kinase binding
GO:0030828 IEA positive regulation of cGMP biosynthetic process
GO:0042417 IEA dopamine metabolic process
GO:0042562 IEA hormone binding
GO:0043235 ISO receptor complex
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0050880 IEA regulation of blood vessel size

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018750 NPR1 (1 of 2) natriuretic peptide receptor 1 protein_coding Danio_rerio
ENSDARG00000031751 npr1a natriuretic peptide receptor 1a protein_coding Danio_rerio
ENSG00000169418 NPR1 natriuretic peptide receptor 1 protein_coding Homo_sapiens

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